N-(1-ANILINONAPHTHYL-4)-MALEIMIDE Chemical Properties

Melting point:

207 °C

Boiling point:

454.02°C (rough estimate)

Density 

1.2303 (rough estimate)

refractive index 

1.5700 (estimate)

pka

3.50±0.30(Predicted)

CAS DataBase Reference

50539-45-2

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

F 

8-10-21

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

N-(1-ANILINONAPHTHYL-4)-MALEIMIDE Usage And Synthesis

Chemical Properties

red powder

Uses

N-(4-Anilino-1-naphthyl)maleimide is a fluorescent probe that can be used to detect thiol groups in proteins. N-(4-Anilino-1-naphthyl)maleimide reacts with thiol groups and immediately produces a stable fluorescent compound with the λex=355 nm, λem=448 nm[1].

References

[1] T Honda, et al. Characterization of the reactivity of sulphydryl groups in tryptophanase by a dual-monitoring high-performance liquid chromatographic system with a site-directed fluorescent reagent. J Chromatogr. 1986 Dec 26;371:353-60. DOI:10.1016/s0021-9673(01)94718-1
[2] S Chaen, et al. Fluorescence properties and contraction characteristics of ANM (N-(1-anilinonaphthyl-4)maleimide)-labeled rabbit psoas muscle fibers. J Biochem. 1985 Oct;98(4):939-47. DOI:10.1093/oxfordjournals.jbchem.a135374

N-(1-ANILINONAPHTHYL-4)-MALEIMIDE(50539-45-2)Related Product Information

• Maleimide
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• 1,4-DIAMINONAPHTHALENE
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• N,N-DIETHYL-1-NAPHTHYLAMINE
• ACETAMIDE, N-(4-AMINO-1-NAPHTHYL)-
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• N-(1-NAPHTHYL) ACRYLAMIDE
• Formamide,N-(4-aminophenyl)-N-methyl-
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• N-(1-ANILINONAPHTHYL-4)-MALEIMIDE
• N-(4-AMINOPHENYL)MALEIMIDE
• N-(4-ANILINOPHENYL)MALEIMIDE
• N,N-Dimethyl-1-naphthylamine