DL-3-(3'-Hydroxy)Butylphthalide Chemical Properties

Boiling point:

369.4±35.0 °C(Predicted)

Density 

1.181±0.06 g/cm3(Predicted)

storage temp. 

Storage temp. 2-8°C

pka

15.05±0.20(Predicted)

Appearance

Colorless to light yellow Liquid

DL-3-(3'-Hydroxy)Butylphthalide Usage And Synthesis

Uses

10-OH-NBP-d4 is deuterium labeled 10-OH-NBP. 10-OH-NBP is a Butylphthalide (3-n-Butylphthalide; NBP; HY-B0647) hydroxylated metabolite and can penetrates the blood-brain barrier (BBB). Butylphthalide exerts neuroprotective effects and has potential for cerebral ischemia research[1].

References

[1] Xing-xing Diao, et al. Isomer-selective distribution of 3-n-butylphthalide (NBP) hydroxylated metabolites, 3-hydroxy-NBP and 10-hydroxy-NBP, across the rat blood-brain barrier. Acta Pharmacol Sin. 2015 Dec;36(12):1520-7. DOI:10.1038/aps.2015.64