Marilixibat chloride
Marilixibat chloride Basic information
- Product Name:
- Marilixibat chloride
- Synonyms:
-
- HP-625)
- Lopixibat chloride (LUM-001
- Maralixibat?chloride
- Maralixibat chloride (Lopixibat chloride)
- Maralixibat
- Livmarli
- Lopixibat
- SHP 625
- CAS:
- 228113-66-4
- MF:
- C40H56ClN3O4S
- MW:
- 710.42
- Mol File:
- 228113-66-4.mol
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Marilixibat chloride Chemical Properties
- storage temp.
- Store at -20°C
- form
- Solid
- color
- White to light yellow
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Marilixibat chloride Usage And Synthesis
Description
Marilixibat chloride is an oral small-molecule ileal bile acid transporter (IBAT) inhibitor developed by Mirum Pharmaceuticals and approved by the USFDA for cholestatic pruritus in patients with Alagille syndrome (ALGS). IBAT facilitates reabsorption of bile acids from the ileum and is a key facilitator of bile acid enterohepatic recirculation. Similar to surgical interruption of enterohepatic recirculation, it was shown that inhibition of IBAT with 22 reduced pruritis in patients with ALGS.
Marilixibat chlorideSupplier
Shanghai Chaolan Chemical Technology Center
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- QQ:65489617 15618227136
- Sales@ATKchemical.com
Guangzhou Belka Biological Technology Co., Ltd.
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- +86-18665676617
Wuhan Demeikai Biotechnology Co., Ltd
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- +8618942921723
- info@dmksw.xin
ShangHai ChuanQian Chemcial Technique Centre
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- 15869524721
- 3525679403@qq.com
BEIJING INNO-TECH PHARMIC TECHNOLOGY CO.,LTD
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- 15011485209