5-(4-CHLOROPHENYL)-2 4-DIHYDRO-1 2 4-TR&
5-(4-CHLOROPHENYL)-2 4-DIHYDRO-1 2 4-TR& Basic information
- Product Name:
- 5-(4-CHLOROPHENYL)-2 4-DIHYDRO-1 2 4-TR&
- Synonyms:
-
- s-Triazole-3-thiol, 5-(p-chlorophenyl)-
- 5-(4-CHLOROPHENYL)-2 4-DIHYDRO-1 2 4-TR&
- 5-(p-chlorophenyl)-s-triazole-3-thio
- 5-(p-chlorophenyl)-s-triazole-3-thiol
- 3-(4-Chlorophenyl)-1,2,4-triazole-5-thiol
- Chlorophenyltriazolethiol
- 5-(4-Chlorophenyl)-2,4-dihydro-[1,2,4]-triazole-3-thiol
- 5-(4-Chloro-phenyl)-1H-[1,2,4]triazole-3-thiol
- CAS:
- 26028-65-9
- MF:
- C8H6ClN3S
- MW:
- 211.67
- Product Categories:
-
- TriazolesBuilding Blocks
- Halogenated Heterocycles
- Heterocyclic Building Blocks
- Triazoles
- Mol File:
- 26028-65-9.mol
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5-(4-CHLOROPHENYL)-2 4-DIHYDRO-1 2 4-TR& Chemical Properties
- Melting point:
- 295-299 °C(lit.)
- Boiling point:
- 296.8±42.0 °C(Predicted)
- Density
- 1.55±0.1 g/cm3(Predicted)
- pka
- 8.21±0.20(Predicted)
- form
- solid
- color
- White to light yellow
- InChI
- InChI=1S/C8H6ClN3S/c9-6-3-1-5(2-4-6)7-10-8(13)12-11-7/h1-4H,(H2,10,11,12,13)
- InChIKey
- NHEHIODVWGKDFV-UHFFFAOYSA-N
- SMILES
- N1C(C2=CC=C(Cl)C=C2)=NC(=S)N1
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Safety Information
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- HazardClass
- IRRITANT
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5-(4-CHLOROPHENYL)-2 4-DIHYDRO-1 2 4-TR& Usage And Synthesis
Uses
DCN1-UBC12-IN-4 (compound 5p) is an inhibitor of DCN1-UBC12, with an IC50 greater than 10000 nM, and it exhibits anti-tumor activity[1].
Definition
ChEBI: 5-(4-chlorophenyl)-1,2-dihydro-1,2,4-triazole-3-thione is a member of triazoles.
References
[1] Wenjuan Zhou, et al. Development of phenyltriazole thiol-based derivatives as highly potent inhibitors of DCN1-UBC12 interaction. Eur J Med Chem. 2021 May 5:217:113326. DOI:10.1016/j.ejmech.2021.113326
5-(4-CHLOROPHENYL)-2 4-DIHYDRO-1 2 4-TR&Supplier
Beijing Solarbio Science & Tecnology Co., Ltd. Gold
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- 010-50973130 17801761073
- Gsiyu@solarbio.com
Energy Chemical
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- 021-021-58432009 400-005-6266
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Nanjing Chemlin Chemical Co., Ltd
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- 025-83697070
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Shanghai Xingui Biotechnology Co., Ltd.
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- 15121041756
- xingui2022@126.com
Shanghai Macklin Biochemical Co.,Ltd.
- Tel
- 15221275939
- shenlinxing@macklin.cn
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5-(4-CHLOROPHENYL)-2 4-DIHYDRO-1 2 4-TR&(26028-65-9)Related Product Information
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- SALOR-INT L294519-1EA
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- BENZIMIDIC ACID, HYDRAZIDE
- 5-(4-CHLOROPHENYL)-2 4-DIHYDRO-1 2 4-TR&