1,2,3,7,8-PENTACHLORODIBENZO-P-DIOXIN Chemical Properties

Melting point:

206°C (estimate)

Boiling point:

442.63°C (rough estimate)

Density 

1.7800 (estimate)

refractive index 

1.6610 (estimate)

solubility 

n-nonane: Soluble

EPA Substance Registry System

1,2,3,7,8-Pentachlorodibenzo-p-dioxin (40321-76-4)

Safety Information

RIDADR 

2811

HazardClass 

6.1(a)

PackingGroup 

I

Toxicity

LD50 orl-rat: 206 mg/kg ARTODN 66,471,92

1,2,3,7,8-PENTACHLORODIBENZO-P-DIOXIN Usage And Synthesis

Uses

A toxic polychlorinated dibenzo-p-dioxin detected in domestic meat and poultry.

Definition

ChEBI: 1,2,3,7,8-Pentachlorodibenzodioxin is a polychlorinated dibenzodioxine.

Safety Profile

Poison by ingestion. Questionable carcinogen. When heated to decomposition it emits toxic fumes of Clí.

References

[1] KARIN I. VAN EDE. Differential relative effect potencies of some dioxin-like compounds in human peripheral blood lymphocytes and murine splenic cells[J]. Toxicology letters, 2014, 226 1: Pages 43-52. DOI: 10.1016/j.toxlet.2014.01.026
[2] RAIMO POHJANVIRTA; Jouko T; Mikko Unkila. Comparative Acute Lethality of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), 1,2,3,7,8-Pentachlorodibenzo-p-dioxin and 1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin in the Most TCDD-Susceptible and the Most TCDD-Resistant Rat Strain[J]. Basic Clinical Pharmacology Toxicology, 1993, 73 1: 52-56. DOI: 10.1111/j.1600-0773.1993.tb01958.x
[3] TIMOTHY ZACHAREWSKI. Comparative analysis of polychlorinated dibenzo-p-dioxin and dibenzofuran congeners in Great Lakes fish extracts by gas chromatography-mass spectrometry and in vitro enzyme induction activities[J]. Environmental Science and Technology, 1989, 23 6: 730-735. DOI: 10.1021/es00064a012
[4] M. PAJUREK; S. M; M Warenik Bany. Feed as a source of dioxins and PCBs[J]. Chemosphere, 2022, 308: Article 136243. DOI: 10.1016/j.chemosphere.2022.136243
[5] SUH-WOAN HU; Chang C C; Guo Ping ChangChien. PCDD/Fs levels in indoor environments and blood of workers of three municipal waste incinerators in Taiwan[J]. Chemosphere, 2004, 55 4: Pages 611-620. DOI: 10.1016/j.chemosphere.2003.10.057
[6] TUNG SON VU . Polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in blood samples from historically herbicide-sprayed areas and rural and industrialized unsprayed areas in Vietnam[J]. Chemosphere, 2023, 326: Article 138331. DOI: 10.1016/j.chemosphere.2023.138331

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