1，1-DIMETHYLBIGUANIDE HYDROCHLORIDE Chemical Properties

Melting point:

223-226 °C(lit.)

CAS DataBase Reference

15537-72-1

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-36/38

Safety Statements 

26-36

WGK Germany 

3

RTECS 

DU1800000

1，1-DIMETHYLBIGUANIDE HYDROCHLORIDE Usage And Synthesis

Originator

Diabetex ,Germania

Definition

ChEBI: Metformin hydrochloride is a hydrochloride resulting from the reaction of metformin with one molar equivalent of hydrogen chloride. It has a role as an environmental contaminant, a hypoglycemic agent and a xenobiotic. It contains a metformin(1+).

Manufacturing Process

The boiling mixture of 1,000 L xylene, 450 kg dimethylamine and 840 kg dicyanamide was added 365 kg hydrogene chloride. Yield of biguanide, 1,1- dimethyl-, hydrochloride 1,588 kg (96%). Biguanide, 1,1-dimethyl-, hydrochloride may be recrystallysed from methanol.

Therapeutic Function

Oral hypoglycemic