3' 4'-DICHLOROBENZAMIL CAS#: 1166-01-4

3' 4'-DICHLOROBENZAMIL Basic information

Product Name:

3' 4'-DICHLOROBENZAMIL

Synonyms:

3' 4'-DICHLOROBENZAMIL
3,5-Diamino-6-chloro-N-[[(3,4-dichlorophenyl)methylamino](imino)methyl]-2-pyrazinecarboxamide
Dichlorobenzamil
N-[Imino[(3,4-dichlorophenylmethyl)amino]methyl]-3,5-diamino-6-chloro-2-pyrazinecarboxamide
3,5-bis(azanyl)-6-chloro-N-[N'-[(3,4-dichlorophenyl)methyl]carbamimidoyl]pyrazine-2-carboxamide
3,5-diamino-6-chloro-N-[N'-(3,4-dichlorobenzyl)carbamimidoyl]pyrazinamide
3,5-diamino-6-chloro-N-[N'-[(3,4-dichlorophenyl)methyl]carbamimidoyl]pyrazine-2-carboxamide
3',4'-Dichlorobenzamil HCl

CAS:

1166-01-4

MF:

C13Cl3H12N7O1

MW:

425.1

Mol File:

1166-01-4.mol

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3' 4'-DICHLOROBENZAMIL Chemical Properties

storage temp.: 2-8°C
solubility: DMSO: 30 mg/mL, soluble
form: solid
color: yellow

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Safety Information

WGK Germany: 3

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3' 4'-DICHLOROBENZAMIL Usage And Synthesis

Uses

Dichlorobenzamil (3',4'-Dichlorobenzamil; L-594881) is an effective Na/Ca exchange inhibitor. Dichlorobenzamil significantly inhibits 45Ca uptake mediated by reverse Na/Ca exchange in pancreatic islet cells (IC50 = 18 μM). Dichlorobenzamil can also block K+ channels and voltage-sensitive Ca2+ channels[1].

Definition

ChEBI: 3,5-diamino-N-[amino-[(3,4-dichlorophenyl)methylimino]methyl]-6-chloro-2-pyrazinecarboxamide is a member of pyrazines and a member of guanidines.

References

[1] Plasman P O, et al. Inhibition of Na/Ca exchange in pancreatic islet cells by 3′, 4′-dichlorobenzamil[J]. Biochemical pharmacology, 1991, 41(11): 1759-1768. DOI:10.1016/0006-2952(91)90181-4

3' 4'-DICHLOROBENZAMILSupplier

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com

Shaanxi Dideu Medichem Co. Ltd

Tel: +86-29-81148696 +86-17392712697
Email: 1022@dideu.com

TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn

TargetMol Chemicals Inc.

Tel: +17819995354
Email: marketing@targetmol.com

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