5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE
5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE Basic information
- Product Name:
- 5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE
- Synonyms:
-
- IFLAB-BB F1208-0006
- 5-(4-HYDROXYBENZYLIDENE)BARBITURIC ACID
- 5-(4-HYDROXYBENZYLIDENE)PYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE
- 5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE
- 5-(4-HYDROXYBENZYLIDENE)BARBUTIRIC ACID
- 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(4-hydroxyphenyl)methylene]-
- 5-(4-hydroxyphenyl)methylenehexahydropyrimidine-2,4,6-trione
- MHY-1685
- CAS:
- 27406-31-1
- MF:
- C11H8N2O4
- MW:
- 232.19
- Mol File:
- Mol File
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5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- DMSO : 62.5 mg/mL (269.18 mM; Need ultrasonic)
- form
- Solid
- color
- Light yellow to yellow
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5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE Usage And Synthesis
Biological Activity
MHY-1685, a novel mammalian target of rapamycin (mTOR) inhibitor, provides opportunities to improve hCSC-based myocardial regeneration.
References
[1]. Park JH, et al. Human cardiac stem cells rejuvenated by modulating autophagy with MHY-1685 enhance the therapeutic potential for cardiac repair. Exp Mol Med. 2021 Sep;53(9):1423-1436.
5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONESupplier
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