2-(DIMETHYLSILYL)PYRIDINE Chemical Properties

Boiling point:

175-178 °C(Press: 758 Torr)

Density 

0.92

refractive index 

n20/D 1.499

Flash point:

41 °C

storage temp. 

2-8°C

solubility 

soluble in most common organic solvents.

pka

5.40±0.12(Predicted)

CAS DataBase Reference

21032-48-4

Safety Information

Hazard Codes 

Xi

Risk Statements 

10-36/37/38

Safety Statements 

36-26

RIDADR 

UN 1993 3/PG 3

WGK Germany 

3

2-(DIMETHYLSILYL)PYRIDINE Usage And Synthesis

Physical properties

bp 68–72 °C/20 mm Hg.

Uses

2-Pyridyldimethylsilane is reagent used for metal-catalyzed hydrosilylation of alkynes and alkenes.Presumably because of the presence of catalyst-directing pyridyl group on silicon, 2- pyridyldimethylsilane exhibits greater reactivity in Rh-catalyzed hydrosilylation of alkenes than those of other related hydrosilanes. Moreover, the presence of the basic pyridyl group enables easy product separation and facile catalyst recovery through simple acid/base extraction.

Uses

A useful scaffold for a number of reactions including hydrosilylation, cross-coupling, and olefination.

Preparation

2-Pyridyldimethylsilane can be prepared by reaction of 2-pyridyllithium with chlorodimethylsilane in dry Et2O at ?78°Cunder argon.

2-(DIMETHYLSILYL)PYRIDINE(21032-48-4)Related Product Information

• 2-(DIMETHYLVINYLSILYL)PYRIDINE
• 2-(ALLYLDIMETHYLSILYL)PYRIDINE
• 3-FLUORO-2-TRIMETHYLSILANYL-PYRIDINE
• 2,2'-[METHYLENEBIS(DIMETHYLSILYLENE)]BISPYRIDINE
• 3-METHOXY-2-TRIMETHYLSILYLPYRIDINE
• 4-CHLORO-2-TRIMETHYLSILYLPYRIDINE
• 3-Chloro-2-(trimethylsilyl)pyridine
• 2-(Trimethylsilyl)pyridine
• 2-(DIMETHYLSILYL)PYRIDINE