16,16-DIMETHYL PROSTAGLANDIN E1
16,16-DIMETHYL PROSTAGLANDIN E1 Basic information
- Product Name:
- 16,16-DIMETHYL PROSTAGLANDIN E1
- Synonyms:
-
- 9-OXO-11ALPHA,15R-DIHYDROXY-16,16-DIMETHYL-PROST-13E-EN-1-OIC ACID
- 16,16-dimethylprostaglandin E
- Prost-13-en-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-oxo-, (11alpha,13E,15R)-
- RQOFITYRYPQNLL-ZWSAOQBFSA-N
- 16,16-dimethyl PGE1
- 9-oxo-11α,15R-dihydroxy-16,16-dimethyl-prost-13E-en-1-oic acid
- 16,16-DIMETHYL PROSTAGLANDIN E1
- Prost-13-en-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-oxo-, (11α,13E,15R)-
- CAS:
- 41692-15-3
- MF:
- C22H38O5
- MW:
- 382.53
- Mol File:
- 41692-15-3.mol
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16,16-DIMETHYL PROSTAGLANDIN E1 Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- DMF: >100 mg/ml; DMSO: >50 mg/ml; Ethanol: >50 mg/ml; PBS pH 7.2: >1.6 mg/ml
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16,16-DIMETHYL PROSTAGLANDIN E1 Usage And Synthesis
Description
16,16-dimethyl PGE1 is a metabolically stable synthetic analog of PGE1. It induces human vascular smooth muscle contractions in vitro. It is 2, 3, and 6 times more potent than PGF2α in contracting tracheal, bronchial, and bronchiolar smooth muscle, respectively.1
Definition
ChEBI: 16,16-dimethyl-PGE1 is a prostanoid.
References
1. Karim, S.M.M., Adaikan, P.G., and Kottegoda, S.R. Prostaglandins and human respiratory tract smooth muscle: Structure activity relationship Adv. Prostaglandin Thromboxane Res. 7,969-980(1980).
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