UV Cleavable Biotin-PEG2-Azide Chemical Properties

form 

Solid

color 

Light yellow to light brown

UV Cleavable Biotin-PEG2-Azide Usage And Synthesis

Uses

UV Cleavable Biotin-PEG2-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. UV Cleavable Biotin-PEG2-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

UV Cleavable Biotin-PEG2-Azide(1192802-98-4)Related Product Information

• UV Cleavable Biotin-PEG2-Azide
• UV Cleavable Biotin-PEG2-Alkyne