DMTr-dH2U-amidite
DMTr-dH2U-amidite Basic information
- Product Name:
- DMTr-dH2U-amidite
- Synonyms:
-
- DMTr-dH2U-amidite
- 4(1H)-Pyrimidinone, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-
- 2-Deoxy-2’-deoxy-5’-(4,4’-dimethoxytrityl)uridine-3’-CED phosphoramidite
- CAS:
- 151503-28-5
- MF:
- C39H47N4O7P
- MW:
- 714.79
- Mol File:
- 151503-28-5.mol
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DMTr-dH2U-amidite Chemical Properties
- Boiling point:
- 749.1±70.0 °C(Predicted)
- pka
- 3.45±0.70(Predicted)
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DMTr-dH2U-amidite Usage And Synthesis
Uses
DMTr-dH2U-amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
DMTr-dH2U-amiditeSupplier
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