(1R,2S,4S,5S)-4-[2-IODO-6-(METHYLAMINO)-9H-PURIN-9-YL]-2-(PHOSPHONOOXY)BICYCLO[3.1.0]HEXANE-1-METHANOL DIHYDROGEN PHOSPHATE ESTER TETRAAMMONIUM SALT
(1R,2S,4S,5S)-4-[2-IODO-6-(METHYLAMINO)-9H-PURIN-9-YL]-2-(PHOSPHONOOXY)BICYCLO[3.1.0]HEXANE-1-METHANOL DIHYDROGEN PHOSPHATE ESTER TETRAAMMONIUM SALT Basic information
- Product Name:
- (1R,2S,4S,5S)-4-[2-IODO-6-(METHYLAMINO)-9H-PURIN-9-YL]-2-(PHOSPHONOOXY)BICYCLO[3.1.0]HEXANE-1-METHANOL DIHYDROGEN PHOSPHATE ESTER TETRAAMMONIUM SALT
- Synonyms:
-
- MRS 2500 TETRAAMMONIUM SALT
- (1R,2S,4S,5S)-4-[2-IODO-6-(METHYLAMINO)-9H-PURIN-9-YL]-2-(PHOSPHONOOXY)BICYCLO[3.1.0]HEXANE-1-METHANOL DIHYDROGEN PHOSPHATE ESTER TETRAAMMONIUM SALT
- (1R*,2S*)-4-[2-Iodo-6-(methylamino)-9H-purin-9-yl]-2-(phosphonooxy)bicyclo[3.1.0]hexane-1-methanoldihydrogenphosphateestertetraammoniumsalt
- [(1R,2S,4S,5S)-4-[2-iodo-6-(methylamino)purin-9-yl]-2-phosphonooxy-1-bicyclo[3.1.0]hexanyl]methyl dihydrogen phosphate
- MRS 2500 , CID: 44448831
- Bicyclo[3.1.0]hexane-1-methanol, 4-[2-iodo-6-(methylamino)-9H-purin-9-yl]-2-(phosphonooxy)-, 1-(dihydrogen phosphate), (1R,2S,4S,5S)-
- MRS 2500 tetraammoni
- CAS:
- 779323-43-2
- MF:
- C13H18IN5O8P2
- MW:
- 561.16
- Mol File:
- 779323-43-2.mol
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(1R,2S,4S,5S)-4-[2-IODO-6-(METHYLAMINO)-9H-PURIN-9-YL]-2-(PHOSPHONOOXY)BICYCLO[3.1.0]HEXANE-1-METHANOL DIHYDROGEN PHOSPHATE ESTER TETRAAMMONIUM SALT Chemical Properties
- storage temp.
- Store at -20°C
- Water Solubility
- <56.12mg/ml in Water
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(1R,2S,4S,5S)-4-[2-IODO-6-(METHYLAMINO)-9H-PURIN-9-YL]-2-(PHOSPHONOOXY)BICYCLO[3.1.0]HEXANE-1-METHANOL DIHYDROGEN PHOSPHATE ESTER TETRAAMMONIUM SALT Usage And Synthesis
Uses
MRS 2500 tetraammonium salt is a highly potent and selective antagonist of the platelet P2Y1 receptor. It inhibits ADP-induced aggregation of human platelets.
Biological Activity
Highly potent and selective antagonist of the platelet P2Y 1 receptor (K i = 0.78 nM). Inhibits ADP-induced aggregation of human platelets with an IC 50 value of 0.95 nM. Prevents thrombus formation in vivo .
(1R,2S,4S,5S)-4-[2-IODO-6-(METHYLAMINO)-9H-PURIN-9-YL]-2-(PHOSPHONOOXY)BICYCLO[3.1.0]HEXANE-1-METHANOL DIHYDROGEN PHOSPHATE ESTER TETRAAMMONIUM SALTSupplier
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