1,7-DIAZA-SPIRO[4.5]DECANE-7-CARBOXYLIC ACID TERT-BUTYL ESTER Chemical Properties

storage temp. 

2-8°C(protect from light)

Appearance

Colorless to light yellow Liquid

InChI

InChI=1S/C13H24N2O2/c1-12(2,3)17-11(16)15-9-5-7-13(10-15)6-4-8-14-13/h14H,4-10H2,1-3H3

InChIKey

PDFULYHFVRJQJO-UHFFFAOYSA-N

SMILES

N1C2(CCCN(C(OC(C)(C)C)=O)C2)CCC1

Safety Information

HS Code 

2933998090

1,7-DIAZA-SPIRO[4.5]DECANE-7-CARBOXYLIC ACID TERT-BUTYL ESTER Usage And Synthesis

Uses

tert-Butyl-1,7-diazaspiro[4.5]decane-7-carboxylate is a useful reagent in preparation of spiro heterocycles as phosphodiesterase inhibitors.

Pharmaceutical Applications

The major structure of 1,7-DIAZA-SPIRO[4.5]DECANE-7-CARBOXYLIC ACID TERT-BUTYL ESTER, Spiro[4.5]decane, functions as a key intermediate in organic synthesis, particularly for the preparation of pharmaceutical derivatives. For instance, it has been employed in the synthesis of spiro[4.5]decane-based analogues of 1α,25-dihydroxyvitamin D3, which exhibit potential biological activity relevant to therapeutic applications.[1]

References

[1] Synthesis of Spiro[4.5]decane CF-Ring Analogues of 1α,25-Dihydroxyvitamin D3. Org. Lett. 2006, 8, 19, 4247–4250. DOI:10.1021/ol061575p

1,7-DIAZA-SPIRO[4.5]DECANE-7-CARBOXYLIC ACID TERT-BUTYL ESTER(939793-21-2)Related Product Information

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