6-Methoxy-4-chromanone Chemical Properties

Melting point:

48 °C

Boiling point:

178-180 °C(Press: 23 Torr)

Density 

1.205

storage temp. 

Sealed in dry,Room Temperature

form 

powder to lump

color 

Light yellow to Yellow to Orange

InChI

InChI=1S/C10H10O3/c1-12-7-2-3-10-8(6-7)9(11)4-5-13-10/h2-3,6H,4-5H2,1H3

InChIKey

LQIYOSKKKUPTRP-UHFFFAOYSA-N

SMILES

C1OC2=CC=C(OC)C=C2C(=O)C1

Safety Information

Risk Statements 

43

Safety Statements 

36/37

HS Code 

2932990090

6-Methoxy-4-chromanone Usage And Synthesis

Synthesis

Representative procedure: synthesis of 6-methoxybenzodihydropyran-4-one (7a). 2,3-Dihydro-4H-chromen-4-one (1.20 g, 6.18 mmol) was dissolved in a mixed acetonitrile-water solvent (10 mL, V/V=1:2) followed by the addition of cerium ammonium nitrate (CAN, 5 g, 9.27 mmol). The reaction mixture was heated to 70 °C under stirring, maintained for 30 min and then cooled to room temperature. After completion of the reaction, the mixture was diluted with water and extracted with ether (3 x 20 mL). The organic phases were combined, washed with saturated sodium bicarbonate solution (20 mL), and dried over anhydrous magnesium sulfate. After filtration, the filtrate was concentrated under reduced pressure to afford the title compound 6-methoxybenzodihydropyran-4-one as a yellow oil (0.64 g, 70% yield).

References

[1] Tetrahedron Letters, 2012, vol. 53, # 33, p. 4280 - 4282

6-Methoxy-4-chromanone(5802-17-5)Related Product Information

• 6-METHOXYISOINDOLIN-1-ONE
• 6-METHOXY-CHROMAN-4-YLAMINE HYDROCHLORIDE
• 6-METHOXYCHROMAN-4-OL
• 6-METHOXY-ISOCHROMAN
• 6-METHOXY-INDAN-1-YL AMINE HYDROCHLORIDE
• 6-methoxychroman-4-amine
• 6-Methoxy-4-chromanone
• 6-Methoxy-3-chromanone
• 5-Methoxy-4-chromanone
• 8-Methoxy-3-chromanone
• 8-Methoxy-4-chromanone
• 6-METHOXYFLAVANONE
• 5-Methoxy-3-chromanone
• 7-Methoxy-4-chromanone
• 4-Chromanone
• 6,7-DIMETHOXY-2,2-DIMETHYL-4-CHLOROMANONE
• 6,2'',4''-TRIMETHOXYFLAVANONE
• 5,9,10-TRIMETHOXY-3,3-DIMETHYL-13,13A-DIHYDRO-3H,7AH-PYRANO[2,3-C:6,5-F']DICHROMEN-7-ONE