EPIROPRIM
EPIROPRIM Basic information
- Product Name:
- EPIROPRIM
- Synonyms:
-
- 5-(3,5-DIETHOXY-4-PYRROL-1-YL-BENZYL)-PYRIMIDINE-2,4-DIAMINE
- EPIROPRIM
- EPIROPRIM:5-(3,5-DIETHOXY-4-PYRROL-1-YL-BENZYL)-PYRIMIDINE-2,4-DIAMINE
- 2,4-Diamino-5-[3,5-diethoxy-4-(1H-pyrrol-1-yl)benzyl]pyrimidine
- Ro-11-8958
- Epiroprime
- Fenarimol Impurity 2 (Triarimol)
- CAS:
- 73090-70-7
- MF:
- C19H23N5O2
- MW:
- 353.41822
- Mol File:
- 73090-70-7.mol
More
Less
EPIROPRIM Chemical Properties
- Boiling point:
- 486.84°C (rough estimate)
- Density
- 1.2174 (rough estimate)
- refractive index
- 1.7600 (estimate)
More
Less
EPIROPRIM Usage And Synthesis
Uses
Epiroprim (Ro11-8958) is a selective dihydrofolate reductase (DHFR) inhibitor. Epiroprim displays excellent activity against staphylococci, enterococci, pneumococci, and streptococci[1].
References
[1] H H Locher, et al. Antibacterial activities of epiroprim, a new dihydrofolate reductase inhibitor, alone and in combination with dapsone. Antimicrob Agents Chemother. 1996 Jun;40(6):1376-81. DOI:10.1128/AAC.40.6.1376