GUANOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT
GUANOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT Basic information
- Product Name:
- GUANOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT
- Synonyms:
-
- sp-cgmps triethylammonium salt
- sp-guanosine 3',5'-cyclic monophosphorothioate triethylammonium salt
- Guanosine-3'',5''-cyclic monophosphothioate sodium salt Sp isomer
- Sp-cGMPS triethylammonium salt, Sp-Cyclic 3μ5μ-hydrogen phosphorothioate guanosine triethylammonium salt
- Sp-Cyclic 3′5′-hydrogen phosphorothioate guanosine triethylammonium salt
- SP-GUANOSINE 3',5'-CYCLIC MONOPHOSPHOROTHIOATE TRIETHYLAMINE
- SP-CYCLIC 3',5'-HYDROGEN PHOSPHOROTHIOATE GUANOSINE TRIETHYLAMINE
- SP-CYCLIC 3'5'-HYDROGEN PHOSPOROTHIOATE GUANOSINE TRIETHYLAMINE
- CAS:
- 86562-10-9
- MF:
- C10H12N5O6PS
- MW:
- 361.27
- Mol File:
- 86562-10-9.mol
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GUANOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT Chemical Properties
- storage temp.
- −20°C
- solubility
- H2O: 5 mg/mL
- form
- solid
- color
- white
MSDS
- Language:English Provider:SigmaAldrich
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GUANOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT Usage And Synthesis
Uses
Sp-cGMPS is an activator of cGMP-dependent protein kinases (PKGs). Sp-cGMPS can be used in cardiovascular disease-related research[1].
References
[1] Archer SL,et al. Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase. Proc Natl Acad Sci U S A. 1994 Aug 2;91(16):7583-7. DOI:10.1073/pnas.91.16.7583
[2] Butt E, et al. Inhibition of cyclic GMP-dependent protein kinase-mediated effects by (Rp)-8-bromo-PET-cyclic GMPS. Br J Pharmacol. 1995 Dec;116(8):3110-6. DOI:10.1111/j.1476-5381.1995.tb15112.x
GUANOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALTSupplier
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