Flutonidine
Flutonidine Basic information
- Product Name:
- Flutonidine
- Synonyms:
-
- 2-(5-Fluoro-o-toluidino)-2-imidazoline
- N-(5-Fluoro-2-methylphenyl)-4,5-dihydro-1H-imidazol-2-amine
- ST-600
- N-(5-fluoro-2-Methylphenyl)-2-iMidazolidineiMine
- Flutonidine
- 1H-Imidazol-2-amine, N-(5-fluoro-2-methylphenyl)-4,5-dihydro-
- CAS:
- 28125-87-3
- MF:
- C10H12FN3
- MW:
- 193.22
- Mol File:
- 28125-87-3.mol
More
Less
Flutonidine Chemical Properties
- Boiling point:
- 273.7±50.0 °C(Predicted)
- Density
- 1.26±0.1 g/cm3(Predicted)
- pka
- 9?+-.0.50(Predicted)
More
Less
Flutonidine Usage And Synthesis
Uses
Flutonidine (ST-600) is a Clonidine (HY-12721) analogue that shows antihypertensive and sympatholytic effects. The initial hypertension produced by Flutonidine is due to stimulation of the peripheral α1, α2 adrenoceptors and the subsequent fall in blood pressure is due to the stimulation of central α2 adrenoceptors. Flutonidine reduces the arrhythmogenic and lethal effects of ouabain. Flutonidine is promising for research of ventricular arrhythmias caused by cardiac glycosides[1][2].
References
[1] Thomas GP, et al. Effect of flutonidine on ouabain-induced arrhythmias and lethality in guinea-pig. Pharmacol Res. 1993 May-Jun;27(4):365-71. DOI:10.1006/phrs.1993.1036
FlutonidineSupplier
Syntechem Co.,Ltd
- Tel
- info@syntechem.com
HangZhou YuHao Chemical Technology Co., Ltd.
- Tel
- 0571-82693216
- info@yuhaochemical.com
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
TargetMol Chemicals Inc.
- Tel
- 4008200310
- marketing@tsbiochem.com
Adooq Bioscience LLC
- Tel
- 400-025-6535
- sales@adooq.cn