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CERIVASTATIN SODIUM

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CERIVASTATIN SODIUM Basic information

Product Name:
CERIVASTATIN SODIUM
Synonyms:
  • RIVASTATIN
  • sodium 7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-dipropan-2-yl-pyrid in-3-yl]-3,5-dihydroxy-hept-6-enoate
  • LIPOBAY
  • BAYCOL
  • CERIVASTATIN NA
  • CERIVASTATIN, SODIUM SALT
  • 7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-dipropan-2-yl-pyrid in-3-yl]-3,5-dihydroxy-hept-6-enoate
  • (3R,5S,6E)-7-[4-(p-Fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)-3-pyridyl]-3,5-dihydroxy-6-heptenoic acid
CAS:
145599-86-6
MF:
C26H34FNO5
MW:
459.55
Product Categories:
  • Active Pharmaceutical Ingredients
Mol File:
145599-86-6.mol
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CERIVASTATIN SODIUM Chemical Properties

Melting point:
>176oC (dec.)
Boiling point:
646.3±55.0 °C(Predicted)
Density 
1.181±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility 
Ethanol (Slightly), Methanol (Slightly), Water (Slightly)
form 
Solid
pka
pKa 4.38 (H2O t=25 I=0.025) (Uncertain);5.29(H2O t=25 I=0.025) (Uncertain)
color 
White to Off-White
Stability:
Hygroscopic
CAS DataBase Reference
145599-86-6(CAS DataBase Reference)
EPA Substance Registry System
6-Heptenoic acid, 7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(1- methylethyl)-3-pyridinyl]-3,5-dihydroxy-, (3R,5S,6E)- (145599-86-6)
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Safety Information

Hazardous Substances Data
145599-86-6(Hazardous Substances Data)
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CERIVASTATIN SODIUM Usage And Synthesis

Uses

assimilate cholesterol

Definition

ChEBI: (3R,5S)-3,5-dihydroxyhept-6-enoic acid in which the (7E)-hydrogen is substituted by a 4-(4-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyridin-3-yl group. Formerly used (as its sodium salt) to lower cho esterol and prevent cardiovascular disease, it was withdrawn from the market worldwide in 2001 following reports of a severe form of muscle toxicity.

brand name

Baycol (Bayer);Cholstat.

CERIVASTATIN SODIUMSupplier

3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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3bsc@sina.com
LGM Pharma
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1-(800)-881-8210
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inquiries@lgmpharma.com
Beijing HuaMeiHuLiBiological Chemical
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010-56205725
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waley188@sohu.com
Shanghai TaoSu Biochemical Technology Co., Ltd.
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021-33632979
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info@tsbiochem.com
LETOPHARM LIMITED
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+86-21-5821 5861
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sales@letopharm.com