O-(2-AMINOETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENOATE Chemical Properties

Boiling point:

450.3±45.0 °C(Predicted)

Density 

0.930±0.06 g/cm3(Predicted)

storage temp. 

Desiccate at -20°C

pka

7.68±0.10(Predicted)

O-(2-AMINOETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENOATE Usage And Synthesis

Uses

Virodhamine is an endogenous cannabinoid receptor mixed antagonist/agonist.

Definition

ChEBI: O-Arachidonoyl ethanolamine is a fatty acid ester.

Biological Activity

Endogenous cannabinoid receptor mixed agonist/antagonist found in higher concentrations peripherally than anandamide. Full agonist at GPR55 and CB 2 and partial agonist/antagonist at CB 1 (EC 50 values are 12, 381 and 2920 nM at GPR55, CB 2 and CB 1 receptors respectively). Induces hypothermia in vivo . Also available as part of the Cannabinoid Receptor Agonist Tocriset™ and Endocannabinoid Tocriset™ .

O-(2-AMINOETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENOATE(287937-12-6)Related Product Information

• O-(2-AMINOETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENOATE
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