Hordenine
Hordenine Basic information
- Product Name:
- Hordenine
- Synonyms:
-
- 4-(2-Dimethylaminoethyl)phenol
- Hordenine
- 4-(2-(Dimethylamino)ethyl)phenol sulfate (1:1) (salt) dihydrate
- Phenol, 4-(2-(dimethylamino)ethyl)-, sulfate (1:1) (salt), dihydrate
- CAS:
- 62493-39-4
- MF:
- C10H15NO
- MW:
- 165.23
- Product Categories:
-
- Plant Biotechnology
- Mol File:
- 62493-39-4.mol
Hordenine Usage And Synthesis
Uses
Hordenine sulfate (Ordenina sulfate) is an active compound extracted from malted barley that has melanin-inhibiting activity. Hordenine sulfate significantly reduced melanin content and reduced intracellular cAMP levels. Hordenine sulfate inhibits the expression of proteins related to melanogenesis, including microblind transcription factor (MITF), tyrosinase, tyrosinase-related protein (TRP)-1, and TRP-2. Therefore, Hordenine sulfate can be used as an active ingredient to inhibit pigmentation[1].
Definition
ChEBI: Hordenine is a phenethylamine alkaloid. It has a role as a human metabolite and a mouse metabolite.
References
[1] Hordenine, a single compound produced during barley germination, inhibits melanogenesis in human melanocytes DOI:10.1016/j.foodchem.2013.03.017
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