TAS 103
TAS 103 Basic information
- Product Name:
- TAS 103
- Synonyms:
-
- TAS 103
- 6-[[2-(Dimethylamino)ethyl]amino]-3-hydroxy-7H-indeno[2,1-c]quinolin-7-one
- TAS-103 HC1
- TA103(bms-247615)
- TAS-103 base
- BMS-247615
- TAS-103(salt)
- CS-1287
- CAS:
- 174634-08-3
- MF:
- C20H19N3O2
- MW:
- 333.38
- Mol File:
- 174634-08-3.mol
More
Less
TAS 103 Chemical Properties
- Melting point:
- 216-217 °C(Solv: ethanol (64-17-5))
- Boiling point:
- 589.5±50.0 °C(Predicted)
- Density
- 1.350±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 7.88±0.20(Predicted)
More
Less
TAS 103 Usage And Synthesis
Biological Activity
TAS-103 is a dual DNA topoisomerase I/II (topoisomerase I/II) inhibitor for cancer research.
in vivo
TAS-103 (30 mg/kg, iv) causes significant tumor growth suppression in mice bearing Lewis lung carcinoma (LLC) cells, without obvious body weight loss, and the liposomal TAS-103 is more active than free TAS-103.
target
| Topoisomerase I
| Topoisomerase II
|
TAS 103Supplier
Shanghai Boyle Chemical Co., Ltd.
- Tel
- sales@boylechem.com
LETOPHARM LIMITED
- Tel
- +86-21-5821 5861
- sales@letopharm.com
SPIRO PHARMA
- Tel
- eric_feng1954@126.com
ShangHai Biochempartner Co.,Ltd
- Tel
- 177-54423994 17754423994
- 2853530910@QQ.com
Amadis Chemical Company Limited
- Tel
- 571-89925085
- sales@amadischem.com