Basic information Safety Supplier Related

Prinaberel

Basic information Safety Supplier Related

Prinaberel Basic information

Product Name:
Prinaberel
Synonyms:
  • ERB 041
  • 2-(3-Fluoro-4-hydroxyphenyl)- 7-vinylbenzoxazol-5-ol
  • 7-Ethenyl-2-(3-fluoro-4-hydroxyphenyl)-5-benzoxazolol
  • PRINABEREL
  • 2-(3-Fluoro-4-hydroxyphenyl)-7-vinyl-1,3-benzoxazol-5-ol
  • Prinaberel (ERB 041)
  • WAY-202041
  • 5-Benzoxazolol, 7-ethenyl-2-(3-fluoro-4-hydroxyphenyl)-
CAS:
524684-52-4
MF:
C15H10FNO3
MW:
271.24
Product Categories:
  • Aromatics
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pfizer Compounds
  • Pharmaceuticals
Mol File:
524684-52-4.mol
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Prinaberel Chemical Properties

Melting point:
250-252 ºC
Boiling point:
451.6±45.0 °C(Predicted)
Density 
1.413
storage temp. 
room temp
solubility 
DMSO: ≥25mg/mL
form 
powder
pka
7.50±0.20(Predicted)
color 
white to tan
InChIKey
MQIMZDXIAHJKQP-UHFFFAOYSA-N
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22-36
Safety Statements 
26
WGK Germany 
3
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Prinaberel Usage And Synthesis

Chemical Properties

Pale Yellow Solid

Uses

ERB 041 is a potent ERβ agonist; displays >200-fold selectivity for ERβ over ERα (IC50 values are 5 and 1216 nM for human ERβ and ERα; 3.1 and 620 nM for rat ERβ and ERα; and 3.7 and 750 nM for mouse ERβ and ERα respectively).

Uses

Prinaberel is a potent ERβ agonist; displays >200-fold selectivity for ERβ over ERα (IC50 values are 5 and 1216 nM for human ERβ and ERα; 3.1 and 620 nM for rat ERβ and ERα; and 3.7 and 750 nM for mouse ERβ and ERα respectively).

storage

Store at -20°C

PrinaberelSupplier

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