Prinaberel
Prinaberel Basic information
- Product Name:
- Prinaberel
- Synonyms:
-
- ERB 041
- 2-(3-Fluoro-4-hydroxyphenyl)- 7-vinylbenzoxazol-5-ol
- 7-Ethenyl-2-(3-fluoro-4-hydroxyphenyl)-5-benzoxazolol
- PRINABEREL
- 2-(3-Fluoro-4-hydroxyphenyl)-7-vinyl-1,3-benzoxazol-5-ol
- Prinaberel (ERB 041)
- WAY-202041
- 5-Benzoxazolol, 7-ethenyl-2-(3-fluoro-4-hydroxyphenyl)-
- CAS:
- 524684-52-4
- MF:
- C15H10FNO3
- MW:
- 271.24
- Product Categories:
-
- Aromatics
- Heterocycles
- Inhibitors
- Intermediates & Fine Chemicals
- Pfizer Compounds
- Pharmaceuticals
- Mol File:
- 524684-52-4.mol
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Prinaberel Chemical Properties
- Melting point:
- 250-252 ºC
- Boiling point:
- 451.6±45.0 °C(Predicted)
- Density
- 1.413
- storage temp.
- room temp
- solubility
- DMSO: ≥25mg/mL
- form
- powder
- pka
- 7.50±0.20(Predicted)
- color
- white to tan
- InChIKey
- MQIMZDXIAHJKQP-UHFFFAOYSA-N
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Prinaberel Usage And Synthesis
Chemical Properties
Pale Yellow Solid
Uses
ERB 041 is a potent ERβ agonist; displays >200-fold selectivity for ERβ over ERα (IC50 values are 5 and 1216 nM for human ERβ and ERα; 3.1 and 620 nM for rat ERβ and ERα; and 3.7 and 750 nM for mouse ERβ and ERα respectively).
Uses
Prinaberel is a potent ERβ agonist; displays >200-fold selectivity for ERβ over ERα (IC50 values are 5 and 1216 nM for human ERβ and ERα; 3.1 and 620 nM for rat ERβ and ERα; and 3.7 and 750 nM for mouse ERβ and ERα respectively).
storage
Store at -20°C
PrinaberelSupplier
J & K SCIENTIFIC LTD.
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