H-D-PRO-PHE-ARG-CHLOROMETHYLKETONE Chemical Properties

Density 

1.37±0.1 g/cm3(Predicted)

storage temp. 

-15°C

pka

13.01±0.46(Predicted)

form 

Solid

color 

White to off-white

Sequence

{d-Pro}-Phe-{Arg-Chloromethylketone}

H-D-PRO-PHE-ARG-CHLOROMETHYLKETONE Usage And Synthesis

Uses

D-Pro-Phe-Arg-Chloromethylketone, a inhibitor of coagulation factor XII and plasma kallikrein, plays an important role in thrombosis and inflammation[1].

References

[1] Katrin F Nickel, et al. Factor XII as a Therapeutic Target in Thromboembolic and Inflammatory Diseases. Arterioscler Thromb Vasc Biol. 2017 Jan;37(1):13-20. DOI:10.1161/ATVBAHA.116.308595

H-D-PRO-PHE-ARG-CHLOROMETHYLKETONE(88546-74-1)Related Product Information

• H-D-PRO-PHE-ARG-CHLOROMETHYLKETONE
• H-D-PRO-NH2 HCL