2,5-DIMETHOXYTHIOPHENOL Chemical Properties

Melting point:

248.3-252.0 °C (decomp)

Boiling point:

88-90 °C/0.5 mmHg (lit.)

Density 

1.134 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.5860(lit.)

Flash point:

>230 °F

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

Chloroform, Methanol

form 

Oil

pka

6.37±0.48(Predicted)

color 

Clear colorless to Pale Yellow

Sensitive 

Stench

BRN 

1867842

LogP

2.300 (est)

CAS DataBase Reference

1483-27-8(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

RIDADR 

2810

WGK Germany 

3

Hazard Note 

Irritant/Stench

HazardClass 

STENCH

HazardClass 

9

PackingGroup 

III

HS Code 

2930909899

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2,5-DIMETHOXYTHIOPHENOL Usage And Synthesis

Chemical Properties

Clear colorless to Pale Yellow Oil

Uses

2,5-Dimethoxythiophenol is a thiophenol derivative used in the preparation of dihydrofolate reductase inhibitors and potential antitumor agents.

General Description

The s-alkylation of 2,5-dimethoxythiophenol with pentyl bromide and heptyl bromide was studied.

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