NO-ASPIRIN 1
NO-ASPIRIN 1 Basic information
- Product Name:
- NO-ASPIRIN 1
- Synonyms:
-
- 2-(ACETYLOXY)-3-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID
- NCX 4016
- NO-ASPIRIN 1
- 2-AcetyloxybenzoicAcid3-NitrooxymethylphenylEster
- nitroaspirin
- [3-(nitrooxymethyl)phenyl] 2-acetyloxybenzoate
- 3-(NitroxyMethyl)phenyl 2-acetoxybenzoate
- 2-Acetoxybenzoate-2-(1-nitroxymethyl)phenyl ester
- CAS:
- 175033-36-0
- MF:
- C16H13NO7
- MW:
- 331.28
- Product Categories:
-
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Aromatics Compounds
- Aromatics
- Inhibitors
- Nitric Oxide Reagents
- Mol File:
- 175033-36-0.mol
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NO-ASPIRIN 1 Chemical Properties
- Melting point:
- 61-62°C
- Boiling point:
- 499.3±40.0 °C(Predicted)
- Density
- 1.347±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- form
- powder
- color
- white to beige
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NO-ASPIRIN 1 Usage And Synthesis
Chemical Properties
Off-White Solid
Definition
ChEBI: 2-acetyloxybenzoic acid [3-(nitrooxymethyl)phenyl] ester is a carbonyl compound.
Biological Activity
NCX 4016 (nitroaspirin) is nitroderivative of aspirin th at combines cyclooxygenase inhibitor with an NO donor. NCX 4016 improves postischemic ventricular dysfunction and to reduce myocardial infarct size in rabbit.', 'NCX-4016 can prevent the progression of cisplatin-resistant human ovarian cancer xenografts in mice. It can also regulate the expression of B-cell lymphoma 2 (Bcl-2) proteins in ovarian cancer cells. Hence, NCX-4016 is considered a promising therapeutic option against carcinoma.
NO-ASPIRIN 1Supplier
J & K SCIENTIFIC LTD.
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- 010-82848833 400-666-7788
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Chemsky(shanghai)International Co.,Ltd.
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- 021-50135380
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Guangzhou Isun Pharmaceutical Co., Ltd
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- 020-39119399 18927568969
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Beijing Jin Ming Biotechnology Co., Ltd.
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- 010-60605840 18892239720
- psaitong@jm-bio.com
Shenzhen SUNGENING Bio-Medical Co., Ltd.
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- 0755-28967200 13631290199
- wxf@sungening.com