Basic information Safety Supplier Related

NO-ASPIRIN 1

Basic information Safety Supplier Related

NO-ASPIRIN 1 Basic information

Product Name:
NO-ASPIRIN 1
Synonyms:
  • 2-(ACETYLOXY)-3-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID
  • NCX 4016
  • NO-ASPIRIN 1
  • 2-AcetyloxybenzoicAcid3-NitrooxymethylphenylEster
  • nitroaspirin
  • [3-(nitrooxymethyl)phenyl] 2-acetyloxybenzoate
  • 3-(NitroxyMethyl)phenyl 2-acetoxybenzoate
  • 2-Acetoxybenzoate-2-(1-nitroxymethyl)phenyl ester
CAS:
175033-36-0
MF:
C16H13NO7
MW:
331.28
Product Categories:
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Aromatics Compounds
  • Aromatics
  • Inhibitors
  • Nitric Oxide Reagents
Mol File:
175033-36-0.mol
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NO-ASPIRIN 1 Chemical Properties

Melting point:
61-62°C
Boiling point:
499.3±40.0 °C(Predicted)
Density 
1.347±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
form 
powder
color 
white to beige
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NO-ASPIRIN 1 Usage And Synthesis

Chemical Properties

Off-White Solid

Definition

ChEBI: 2-acetyloxybenzoic acid [3-(nitrooxymethyl)phenyl] ester is a carbonyl compound.

Biological Activity

NCX 4016 (nitroaspirin) is nitroderivative of aspirin th at combines cyclooxygenase inhibitor with an NO donor. NCX 4016 improves postischemic ventricular dysfunction and to reduce myocardial infarct size in rabbit.', 'NCX-4016 can prevent the progression of cisplatin-resistant human ovarian cancer xenografts in mice. It can also regulate the expression of B-cell lymphoma 2 (Bcl-2) proteins in ovarian cancer cells. Hence, NCX-4016 is considered a promising therapeutic option against carcinoma.

NO-ASPIRIN 1Supplier

J & K SCIENTIFIC LTD.
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