O-TOLYLHYDRAZINE HYDROCHLORIDE Chemical Properties

Melting point:

190 °C (dec.)(lit.)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

alcohol: soluble

form 

Crystalline Powder

color 

Beige

Sensitive 

Hygroscopic

Merck 

14,9542

BRN 

3655929

CAS DataBase Reference

635-26-7(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

20/21/22-36/37/38

Safety Statements 

26-36/37/39

RIDADR 

UN 2811 6.1/PG 3

WGK Germany 

3

Hazard Note 

Harmful/Irritant

HazardClass 

6.1

PackingGroup 

III

HS Code 

29280090

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

O-TOLYLHYDRAZINE HYDROCHLORIDE Usage And Synthesis

Chemical Properties

beige crystalline powder

Uses

o-Tolylhydrazine Hydrochloride is a reagent used in the organic syntheses such as opioid receptor antagonists as well as adenosine receptor antagonists as well as adenosine receptor antagonists.

Uses

o-Tolylhydrazine hydrochloride has been used in the preparation of o-tolylhydrazone of D-galactose.

Synthesis

General procedure for the synthesis of o-tolylhydrazine hydrochloride from o-tolylhydrazine: purified o-tolylhydrazine (100 g) was dissolved in 69 mL of 37% hydrochloric acid, and the reaction solution was stirred at 65°C until crystallization. The reaction mixture was then cooled to 20°C and the solid product was collected by filtration. The filter cake was washed with acetone and dried to give 110 g of o-tolylhydrazine hydrochloride product with 99.2% purity and 39.5% yield.

References

[1] Patent: CN107814750, 2018, A. Location in patent: Paragraph 0026; 0027; 0035; 0036; 0046

O-TOLYLHYDRAZINE HYDROCHLORIDE(635-26-7)Related Product Information

• 2-Toluenesulfonyl isocyanate
• 2-(Trifluoromethyl)benzaldehyde
• Methyl 2-methoxybenzoate
• 2-Tolylboronic acid
• o-Toluoyl chloride
• o-Toluic acid
• 2-Methylphenylacetic acid
• 2-Methylbenzaldehyde
• o-Anisaldehyde
• 2'-Methylacetophenone
• 2,4,6-TRIMETHYLPHENYLHYDRAZINE HYDROCHLORIDE
• O-TOLYLHYDRAZINE HYDROCHLORIDE
• 4-METHYLPHENYLHYDRAZINE HCL,4-TOLYLHYDRAZINE HYDROCHLORIDE,P-TOLYLHYDRAZINE HYDROCHLORIDE
• 3-CHLORO-4-TOLYLHYDRAZINE HYDROCHLORIDE,3-CHLORO-P-TOLYLHYDRAZINE HYDROCHLORIDE 98%,3-CHLORO-P-TOLYLHYDRAZINE HYDROCHLORIDE
• 2,6-Dibromo-4-tolylhydrazine hydrochloride
• 5-Bromo-2-Methylphenylhydrazine HCl
• M-TOLYLHYDRAZINE HYDROCHLORIDE,meta-tolylhydrazine hydrochloride,3-TOLYLHYDRAZINE HYDROCHLORIDE,M-METHYLPHENYLHYDRAZINE HCL,3-METHYLPHENYLHYDRAZINE HCL
• 4-(1,2,4-TRIAZOLE-1-YL)METHYLPHENYLHYDRAZINE HCL