Basic information Safety Supplier Related

2'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE LITHIUM SALT

Basic information Safety Supplier Related

2'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE LITHIUM SALT Basic information

Product Name:
2'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE LITHIUM SALT
Synonyms:
  • 2'-DEOXYCYTIDINE-5'-TRIPHOSPHORIC ACID, LITHIUM
  • 2'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE LITHIUM SALT
  • DCTP, LI
  • DCTP LI-SALT
  • Cytidine 5'-(tetrahydrogen triphosphate), 2'-deoxy-
  • 2'-deoxycytidine triphosphate
  • [[[5-(4-amino-2-oxo-pyrimidin-1-yl)-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphonic acid
  • 2''-DEOXYCYTIDINE 5''-TRIPHOSPHATE (DCTP)
CAS:
2056-98-6
MF:
C9H16N3O13P3
MW:
467.16
EINECS:
218-153-9
Product Categories:
  • Nucleic acids
Mol File:
2056-98-6.mol
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2'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE LITHIUM SALT Chemical Properties

Boiling point:
811.5±75.0 °C(Predicted)
Density 
2.38±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
0.80±0.50(Predicted)
form 
Stabilized Aqueous Solution
color 
White to off-white
Water Solubility 
Water : ≥ 35 mg/mL (74.92 mM)
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2'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE LITHIUM SALT Usage And Synthesis

Uses

Isotope labelled 2’-Deoxycytidine 5’-Triphosphate Triethylamine, a labelled metabolite of 2’-Deoxycytidine, a nucleoside triphosphate that is used whenever DNA is synthesized, such as in the polymerase chain reaction.

Definition

ChEBI: DCTP is a 2'-deoxycytidine phosphate having cytosine as the nucleobase. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a 2'-deoxycytidine phosphate and a pyrimidine 2'-deoxyribonucleoside 5'-triphosphate. It is a conjugate acid of a dCTP(3-).

Biological Activity

Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used in DNA synthesis. Deoxycytidine triphosphate can be used in real-time PCR, cDNA synthesis and DNA sequencing research.

in vitro

Assays of thirteen cell lines, derived from mouse lymphomas, myelomas, myeloid tumors, and a mastocytoma, for sensitivity to growth inhibition by 1-β-D-arabinofuranosylcytosine (ara-C) revealed a spectrum between the most and least sensitive which differed 100-fold from each other. An inverse correlation between sensitivity and cellular Deoxycytidine triphosphate (2′-Deoxycytidine-5′-triphosphate, dCTP) content is found, and this suggested that sensitivity of cells might be increased if the dCTP content was lowered during cell exposure to ara-C.
Deoxycytidine triphosphate trisodium salt is a phosphoethanolamine cytidylyltransferase substrate.

target

Human Endogenous Metabolite

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