SALOR-INT L135356-1EA
SALOR-INT L135356-1EA Basic information
- Product Name:
- SALOR-INT L135356-1EA
- Synonyms:
-
- SALOR-INT L135356-1EA
- DCHC
- 3-(2,4-Dichlorophenyl)-7-hydroxy-4H-chromen-4-one
- DCHC >=98% (HPLC), solid
- 4H-1-Benzopyran-4-one, 3-(2,4-dichlorophenyl)-7-hydroxy-
- CAS:
- 302953-06-6
- MF:
- C15H8Cl2O3
- MW:
- 307.13
- Mol File:
- Mol File
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SALOR-INT L135356-1EA Chemical Properties
- Boiling point:
- 498.5±45.0 °C(Predicted)
- Density
- 1.523±0.06 g/cm3(Predicted)
- solubility
- DMSO: >20mg/mL
- pka
- 6.72±0.20(Predicted)
- form
- solid
- color
- yellow
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SALOR-INT L135356-1EA Usage And Synthesis
Uses
DCHC is a SIRT1 activator but does not induce SIRT1 expression. DCHC can be used for mitochondrial damage related studies[1].
Definition
ChEBI: 3-(2,4-dichlorophenyl)-7-hydroxy-4H-chromen-4-one is a member of the class of 7-hydroxyisoflavones that is 3-phenyl-4H-chromen-4-one which is substituted by a hydroxy group at position 7 and chloro groups at positions 2' and 4'. It is a SIRT1 activator. It is a member of 7-hydroxyisoflavones and a dichlorobenzene.
IC 50
SIRT1
References
[1] Rasbach KA, et al. Isoflavones promote mitochondrial biogenesis. J Pharmacol Exp Ther. 2008 May;325(2):536-43. DOI:10.1124/jpet.107.134882