O-PHOSPHO-L-THREONINE Chemical Properties

Melting point:

169 °C

Boiling point:

454.0±55.0 °C(Predicted)

Density 

1.671±0.06 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

NH₄OH 1 M: 0.1 g/mL, clear, colorless

pka

1.73±0.10(Predicted)

form 

A solid

BRN 

1727078

Safety Information

WGK Germany 

3

F 

10

MSDS

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O-PHOSPHO-L-THREONINE Usage And Synthesis

Definition

ChEBI: O-phospho-L-threonine is a L-threonine derivative phosphorylated at the side-chain hydroxy function. It has a role as an Escherichia coli metabolite. It is a L-threonine derivative, a non-proteinogenic L-alpha-amino acid and an O-phosphoamino acid. It is a conjugate acid of an O-phosphonato-L-threonine(2-).

Biochem/physiol Actions

O-Phospho-L-threonine is an amino acid derivative.

Purification Methods

Dissolve the phosphate in the minimum volume of H2O, add charcoal, stir for a few minutes, filter and apply onto a column of Dowex 50W (H+ form), then elute with 2N HCl. Evaporate the eluates under reduced pressure whereby the desired fraction produces crystals of the phosphate which can be recrystallised from H2O/MeOH mixtures and the crystals are then dried in vacuo over P2O5 at ~80o. [de Verdier Acta Chem Scand 7 196 1953, Beilstein 4 IV 3175.]

O-PHOSPHO-L-THREONINE(1114-81-4)Related Product Information

• 3-Hydroxybutyric acid
• O-PHOSPHO-DL-THREONINE
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• THREONINE PHOSPHATE, L-, [14C(U)]
• FMOC-THR(PO3ME2)-OH
• Fmoc-O-(benzylphospho)-L-threonine
• FMOC-O-PHOSPHO-L-THREONINE
• O-PHOSPHO-L-THREONINE