C6 NBD SAFINGOL Chemical Properties

storage temp. 

−20°C

solubility 

DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml; Ethanol: 0.5 mg/ml

form 

A crystalline solid

InChIKey

GEZLBJRDZRUTOE-AHKZPQOWSA-N

SMILES

C(N[C@@H](CO)[C@H](O)CCCCCCCCCCCCCCC)(=O)CCCCCNC1C2C(C([N+]([O-])=O)=CC=1)=NON=2

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

C6 NBD SAFINGOL Usage And Synthesis

Description

C6 NBD ceramide is a biologically active fluorescent analog of short chain, membrane-permeable ceramides. It is as effective as C6 ceramide in the inhibition of viral glycoprotein transport through the Golgi. C6 NBD ceramide has been used as a fluorescent substrate for the activity of UDP-glucose:ceramide glucosyltransferase and to demonstrate the translocation of glucocerebroside and sphingomyelin from the Golgi to the plasma membrane. C6 NBD dihydro ceramide (d18:0/6:0) is structurally identical to C6 NBD ceramide, except it contains a saturated bond in the C-4/C-5 position of the sphingosine backbone.