Basic information Safety Supplier Related

RG-13022

Basic information Safety Supplier Related

RG-13022 Basic information

Product Name:
RG-13022
Synonyms:
  • 3-Pyridineacetonitrile, α-[(3,4-dimethoxyphenyl)methylene]-, (αZ)-
  • (Z)-RG-13022
CAS:
149286-90-8
MF:
C16H14N2O2
MW:
266.29456
Mol File:
149286-90-8.mol
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RG-13022 Chemical Properties

Boiling point:
423.8±45.0 °C(Predicted)
Density 
1.172±0.06 g/cm3(Predicted)
solubility 
DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml; Ethanol: 2 mg/ml
form 
A crystalline solid
pka
3.74±0.12(Predicted)
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RG-13022 Usage And Synthesis

Description

Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds that act as PTK blockers. PTK inhibitors that preferentially inhibit the epidermal growth factor (EGF) receptor kinase block EGF-dependent cell proliferation. Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds that act as PTK blockers. PTK inhibitors that preferentially inhibit the epidermal growth factor (EGF) receptor kinase block EGF-dependent cell proliferation. RG-13022 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 1 μM in HT-22 cells.

Definition

ChEBI: 3-(3,4-dimethoxyphenyl)-2-(3-pyridinyl)-2-propenenitrile is a dimethoxybenzene.

RG-13022Supplier

Nanjing Tengyi Biotechnology Co., Ltd
Tel
025-58851786 17714337195
Email
sales@tybiochem.com
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
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RG-13022(149286-90-8)Related Product Information