Basic information Safety Supplier Related

1-[(4-CHLOROPHENYL)METHYL]-1H-INDOLE-3-METHANOL

Basic information Safety Supplier Related

1-[(4-CHLOROPHENYL)METHYL]-1H-INDOLE-3-METHANOL Basic information

Product Name:
1-[(4-CHLOROPHENYL)METHYL]-1H-INDOLE-3-METHANOL
Synonyms:
  • 1-[(4-CHLOROPHENYL)METHYL]-1H-INDOLE-3-METHANOL
  • 1H-INDOLE-3-METHANOL, 1-[(4-CHLOROPHENYL)METHYL]-
  • [1-(4-Chloro-benzyl)-1H-indol-3-yl]-methanol
  • NSC 741909
  • NSC741909
  • NSC-741909
  • NSC741909,NSC 741909
  • Oncrasin-60
CAS:
92407-91-5
MF:
C16H14ClNO
MW:
271.74
Mol File:
92407-91-5.mol
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1-[(4-CHLOROPHENYL)METHYL]-1H-INDOLE-3-METHANOL Chemical Properties

form 
Solid
color 
White to off-white
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1-[(4-CHLOROPHENYL)METHYL]-1H-INDOLE-3-METHANOL Usage And Synthesis

Description

NSC-741909 is an anticancer agent. It acts by suppressing the growth of several cell lines derived from lung, colon, breast, ovarian, and kidney cancers.

Uses

Oncrasin-60 (NSC-741909) is a compound with antitumor activity that is active against multiple cancer cell lines in vitro and can induce tumor regression in vivo, with its mechanism involving JNK activation and STAT3 inhibition.

References

[1] Antitumor activity of a novel oncrasin analogue is mediated by JNK activation and STAT3 inhibition DOI:10.1371/journal.pone.0028487

1-[(4-CHLOROPHENYL)METHYL]-1H-INDOLE-3-METHANOLSupplier

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