Basic information Safety Supplier Related

(3alpha,5beta,7alpha,12alpha)-3,7,12-Tris(formyloxy)cholan-24-oic acid

Basic information Safety Supplier Related

(3alpha,5beta,7alpha,12alpha)-3,7,12-Tris(formyloxy)cholan-24-oic acid Basic information

Product Name:
(3alpha,5beta,7alpha,12alpha)-3,7,12-Tris(formyloxy)cholan-24-oic acid
Synonyms:
  • (3alpha,5beta,7alpha,12alpha)-3,7,12-Tris(formyloxy)cholan-24-oic acid
  • 3a,7a,12a-tri(forMyloxy)-5b-cholanic acid
  • OHJFKWAMNYLNEV-OCCHXLOTSA-N
  • 3α,7α,12α-tri(forMyloxy)-5β-cholan-24-oic acid
  • (3α,5β,7α,12α)-3,7,12-Tris(forMyloxy)cholan-24-oic acid
  • Cholan-24-oic acid, 3,7,12-tris(formyloxy)-, (3α,5β,7α,12α)-
  • Tri-O-formylcholic Acid
  • 3α,7α,12α-tri(formyloxy)-5β-cholan-24-oic acid
CAS:
2097-89-4
MF:
C27H40O8
MW:
492.6
Mol File:
2097-89-4.mol
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(3alpha,5beta,7alpha,12alpha)-3,7,12-Tris(formyloxy)cholan-24-oic acid Chemical Properties

Melting point:
201-203 °C
Boiling point:
593.7±50.0 °C(Predicted)
Density 
1.21
storage temp. 
2-8°C
pka
4.76±0.10(Predicted)
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(3alpha,5beta,7alpha,12alpha)-3,7,12-Tris(formyloxy)cholan-24-oic acid Usage And Synthesis

Uses

Tri-O-formylcholic Acid is an intermediate used in the synthesis of 3α,7α,12α-Trihydroxycoprostanic Acid-d3 (T795157), which is a labelled analogue of 3α,7α,12α-Trihydroxycoprostanic Acid (T795155), a precursor of Cholic Acid (C432600), it undergoes side chain oxidation during the synthesis of bile acids. It was found that Zellweger’s syndrome patients have abnormal mitochondrial structure, the organelle that is responsible for the side chain oxidation, and as a consequence, excess amounts of 3α,7α,12α-Trihydroxycoprostanic Acid.

(3alpha,5beta,7alpha,12alpha)-3,7,12-Tris(formyloxy)cholan-24-oic acidSupplier

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