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12-AMino Minocycline

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12-AMino Minocycline Basic information

Product Name:
12-AMino Minocycline
Synonyms:
  • (4S,4aS,5aR,12aS)-12-AMino-4,7-bis(diMethylaMino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12a-trihydroxy-1,11-dioxo-2-naphthacenecarboxaMide
  • 12-AMino Minocycline
  • Minocycline EP Impurity E/Imino Delta Minocycline/12-Amino Minocycline/(4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12a-trihydroxy-12-imino-1,11-dioxo-1,4,4a,5,5a,6,11,11a,12,12a-decahydrotetracene-2-carboxamide
  • 12-Amino Minocycline (~90%)
  • Minocycline Impurity E (Mixture of Diastereomers)
  • 2-Naphthacenecarboxamide, 12-amino-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12a-trihydroxy-1,11-dioxo-, (4S,4aS,5aR,12aS)-
  • Minocycline Impurity E
  • 12-Imino Delta Minocycline
CAS:
864073-42-7
MF:
C23H28N4O6
MW:
456.49
Product Categories:
  • Amines
  • Aromatics
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
Mol File:
864073-42-7.mol
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12-AMino Minocycline Chemical Properties

Melting point:
>105°C (dec.)
Boiling point:
794.5±60.0 °C(Predicted)
Density 
1.51±0.1 g/cm3(Predicted)
storage temp. 
Amber Vial, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
4.50±1.00(Predicted)
color 
Yellow to Dark Orange
Stability:
Light Sensitive
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12-AMino Minocycline Usage And Synthesis

Uses

12-AMino Minocycline is an impurity of Minocycline (M344800),it is used in the preparation of calpain inhibitors.

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