FluoroMalonaldehydic Acid
FluoroMalonaldehydic Acid Basic information
- Product Name:
- FluoroMalonaldehydic Acid
- Synonyms:
-
- 2-Fluoro-3-oxopropanoic Acid
- Fluoromalonaldehydic Acid Discontinued
- Propanoic acid, 2-fluoro-3-oxo-
- Fluorouracil Impurity 10
- Fluoromalonaldehydic Acid (>85%)
- FluoroMalonaldehydic Acid Impurity 8
- CAS:
- 58629-87-1
- MF:
- C3H3FO3
- MW:
- 106.05
- Product Categories:
-
- Aliphatics
- Intermediates & Fine Chemicals
- Metabolites & Impurities
- Pharmaceuticals
- Mol File:
- 58629-87-1.mol
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FluoroMalonaldehydic Acid Chemical Properties
- Melting point:
- >52°C (subl.)
- storage temp.
- Hygroscopic, -20°C Freezer, Under Inert Atmosphere
- solubility
- Aqueous Acid (Sparingly), Methanol (Very Slightly, Heated)
- form
- Solid
- color
- Off-White to Brown
- Stability:
- Hygroscopic, Light Sensitive, Temperature Sensitive
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FluoroMalonaldehydic Acid Usage And Synthesis
Uses
A degradation product of 2,2''-Anhydro-1-β-D-arabinofuranosyl-5-fluorocytosine and 1-β-D-Arabinofuranosyl-5-fluorocytosine in rats. Fluoromalonaldehydic acid would be oxidized in vivo to fluoromalonic acid and utimately to fluoroacetate, compounds known to inhibit the Krebs cycle.
Uses
A degradation product of 2,2'-Anhydro-1-β-D-arabinofuranosyl-5-fluorocytosine and 1-β-D-Arabinofuranosyl-5-fluorocytosine in rats. Fluoromalonaldehydic acid would be oxidized in vivo to fluoromalonic acid and utimately to fluoroacetate, compounds known to inhibit the Krebs cycle.
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