3-Azetidinol, 1-[3-(2-benzo[b]thien-5-ylethoxy)propyl]-, (2Z)-2-butenedioate (1:1)
3-Azetidinol, 1-[3-(2-benzo[b]thien-5-ylethoxy)propyl]-, (2Z)-2-butenedioate (1:1) Basic information
- Product Name:
- 3-Azetidinol, 1-[3-(2-benzo[b]thien-5-ylethoxy)propyl]-, (2Z)-2-butenedioate (1:1)
- Synonyms:
-
- Edonerpic maleate
- 3-Azetidinol, 1-[3-(2-benzo[b]thien-5-ylethoxy)propyl]-, (2Z)-2-butenedioate (1:1)
- T-817 maleate
- Edonerpic
- Edonerpic maleate (T-817 maleate
- T-817MA))
- Inhibitor,β-amyloid peptide,Abeta,Amyloid-β,T 817,Edonerpic,T817,Edonerpic maleate,T-817,inhibit
- Edenorpic maleate
- CAS:
- 519187-97-4
- MF:
- C20H25NO6S
- MW:
- 407.4806
- Mol File:
- 519187-97-4.mol
3-Azetidinol, 1-[3-(2-benzo[b]thien-5-ylethoxy)propyl]-, (2Z)-2-butenedioate (1:1) Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- DMSO:90.5(Max Conc. mg/mL);222.1(Max Conc. mM)
Ethanol:40.0(Max Conc. mg/mL);98.16(Max Conc. mM)
Water:90.5(Max Conc. mg/mL);222.1(Max Conc. mM) - form
- A solid
- color
- White to off-white
3-Azetidinol, 1-[3-(2-benzo[b]thien-5-ylethoxy)propyl]-, (2Z)-2-butenedioate (1:1) Usage And Synthesis
Uses
3-Azetidinol, 1-[3-(2-benzo[b]thien-5-ylethoxy)propyl]-, (2Z)-2-butenedioate (1:1) can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development process and chemical production process.
in vivo
The post hoc test indicates that the mean density of PSA-positive cells is significantly larger in the vehicle and Aβ infusion+high-dose Edonerpic maleate (T-817MA) groups than that in the Aβ infusion control group (P<0.01). The results indicate that the vehicle and Aβ infusion+high-dose Edonerpic maleate groups display efficient learning in the place learning task (PLT), while these two groups also display vigorous neurogenesis. Treatment with Edonerpic maleate and donepezil does not increase the mean density of normal granule cells; there are no significant differences in the mean granule cell density among the Aβ infusion control, Aβ infusion+high-dose Edonerpic maleate, Aβ infusion+low-dose Edonerpic maleate and Aβ infusion+donepezil groups[2].
3-Azetidinol, 1-[3-(2-benzo[b]thien-5-ylethoxy)propyl]-, (2Z)-2-butenedioate (1:1)Supplier
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