Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Organic Chemistry >  Nitrogen Compounds >  5(6)-Nitrofluorescein

5(6)-Nitrofluorescein

Basic information Safety Supplier Related

5(6)-Nitrofluorescein Basic information

Product Name:
5(6)-Nitrofluorescein
Synonyms:
  • 5(6)-Nitrofluorescein
  • 3',6'-Dihydroxy-5(or 6)-nitro-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one
  • 3',6'-Dihydroxy-5(or 6)-nitro-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one
CAS:
78512-32-0
MF:
C20H11NO7
MW:
377.30384
Mol File:
78512-32-0.mol
More
Less

5(6)-Nitrofluorescein Chemical Properties

storage temp. 
2-8°C
InChI
InChI=1S/C20H11NO7/c22-11-2-5-15-17(8-11)27-18-9-12(23)3-6-16(18)20(15)14-4-1-10(21(25)26)7-13(14)19(24)28-20/h1-9,22-23H
InChIKey
UACQOMKZFGNRBL-UHFFFAOYSA-N
SMILES
O1C2(C3=C(C=C(O)C=C3)OC3=C2C=CC(O)=C3)C2=CC=C([N+]([O-])=O)C=C2C1=O
More
Less

5(6)-Nitrofluorescein Usage And Synthesis

Uses

5(6)-Nitrofluorescein is the mixture of 5- and 6-nitrofluoresceine isomers. This compound is a useful compound that could be used to synthesize fluorescein 5-isothiocyanate.

Synthesis

A process for the preparation of a mixture (5(6)-Nitrofluorescein) of 3′,6′-dihydroxy-6-nitrospiro[2-benzofuran-3,9′-xanthene]-1-one and 3′,6′-dihydroxy-5-nitrospiro[2-benzofuran-3,9′- xanthene]-1-one comprising the steps of (a) reacting 4-nitrophthalic acid or 4-nitrophthalic anhydride with benzene-1,3-diol in methanesulphonic acid; (b) quenching the reaction in step (a) with a solvent to precipitate product; (c) isolating the precipitate; (d) heating the precipitate in water in order to hydrolyse any methansulphonic acid ester present.

5(6)-NitrofluoresceinSupplier

Suzhouhongxiong Gold
Tel
18051745768 18051745768
Email
Suzhouhongxiong@163.com
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18934348241
Email
sales4.gd@hwrkchemical.com
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883 15367835770
Email
viola@huatengsci.com
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400-6387771-6038 18902104717
Email
sales@heowns.com
More
Less

5(6)-Nitrofluorescein(78512-32-0)Related Product Information