7,11-Diethyl-10-hydroxycaMptothecin CAS#: 947687-01-6

Product Name:

7,11-Diethyl-10-hydroxycaMptothecin

Synonyms:

Irinotecan EP Impurity G
IRINOTECAN EP IMPURITY G (7,11-DIETHYL-10-HYDROXY CAMPTOTHECIN)
(S)-4,8,11-Triethyl-4,9-dihydroxy-1H-pyrano[3’,4’:6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
(S)-4,8,11-triethyl-4,9-dihydroxy-
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4,8,11-triethyl-4,9-dihydroxy-, (4S)-
(S)-4,8,11-triethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione? (Irinotecan Impurity）
Irinotecan EP Impurity G/ Irinotecan Related Compound G (7,11-Diethyl-10-hydroxycamptothecin/ 8,11-Diethyl-9-Hydroxy Camptothecin)
(4S)-4,8,11-Triethyl-4,9-dihydroxy-1H-pyrano[3'',4'':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

CAS:

947687-01-6

MF:

C24H24N2O5

MW:

420.46

Product Categories:

Aromatics, Heterocycles, Impurities, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals

Mol File:

947687-01-6.mol

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Boiling point:: 798.1±60.0 °C(Predicted)
Density: 1.44±0.1 g/cm3(Predicted)
storage temp.: 2-8°C, sealed storage, away from moisture and light
solubility: DMSO (Slightly, Heated)
form: Solid
pka: 9.43±0.40(Predicted)
color: Light Yellow to Yellow
InChI: InChI=1S/C24H24N2O5/c1-4-12-7-18-14(8-20(12)27)13(5-2)15-10-26-19(21(15)25-18)9-17-16(22(26)28)11-31-23(29)24(17,30)6-3/h7-9,27,30H,4-6,10-11H2,1-3H3/t24-/m0/s1
InChIKey: BQAJEBSARMNUPK-DEOSSOPVSA-N
SMILES: N1C2C(=CC(O)=C(CC)C=2)C(CC)=C2CN3C(C=12)=CC1[C@](CC)(O)C(=O)OCC=1C3=O

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7,11-Diethyl-10-hydroxycamptothecin is an impurity of the DNA topoisomerase inhibitor Irinotecan (I767500).

Suzhou Puster Biotechnology Co., Ltd Gold

J & K SCIENTIFIC LTD.

Adamas Reagent, Ltd.

Shanghai TaoSu Biochemical Technology Co., Ltd.

Bide Pharmatech Ltd.

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7,11-Diethyl-10-hydroxycaMptothecin