3α-hydroxy-6-ethyl-7-keto-5β-cholan-24-oic acid Chemical Properties

Boiling point:

561.5±25.0 °C(Predicted)

Density 

1.087±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

soluble in Dichloromethane; Chloroform; Ethyl Acetate; DMSO; Methanol;

form 

Solid

pka

4.76±0.10(Predicted)

color 

White

3α-hydroxy-6-ethyl-7-keto-5β-cholan-24-oic acid Usage And Synthesis

Uses

(3α,5β,6α)-6-Ethyl-3-hydroxy-7-oxo-cholan-24-oic Acid is an intermediate used in the synthesis of 6α-Ethyl Ursodeoxycholic Acid (E932095), which is an epimer of Obeticholic Acid (E899810). Obeticholic Acid is a derivative of the bile acid Chenodeoxycholic Acid (C291900). Obeticholic Acid is a potent activator of the farnesoid X nuclear receptor which reduces liver fat and fibrosis in animal models of fatty liver disease.

3α-hydroxy-6-ethyl-7-keto-5β-cholan-24-oic acid(915038-26-5)Related Product Information

• Obeticholic Impurity 11
• Obeticholic Acid Impurity 7
• NA
• Obeticholic Acid Impurity 12
• Obeticholic Acid Impurity 6
• Obeticholic Acid Impurity 15
• 6alpha-Ethyl-chenodeoxycholic acid
• Glyco Obeticholic acid
• (R)-4-((3R,5S,6S,7S,10S,13R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
• (3α,5β,7α)-6-ethylidene-3,7-dihydroxycholan-24-oic acid
• Tauro Obeticholic acid
• (R)-4-((3R,5S,6S,7R,10S,13R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
• Obeticholic Acid impurity
• (3R,5S,6R,7R,10S,13R)-6-ethyl-17-((R)-5-hydroxypentan-2-yl)-10,13-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
• Cholan-24-oic acid,6-ethylidene-3-hydroxy-7-oxo-,phenylmethyl ester, (3α,5β)-
• Obeticholic Acid
• (E)-3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-oic acid
• 7-ketolithocholic Methyl ester