Basic information Safety Supplier Related

BENZYL METHYL NITROSAMINE

Basic information Safety Supplier Related

BENZYL METHYL NITROSAMINE Basic information

Product Name:
BENZYL METHYL NITROSAMINE
Synonyms:
  • BENZYL METHYL NITROSAMINE
  • N-METHYL-N-BENZYLNITROSAMINE
  • n-methyl-n-nitrosobenzylamine
  • N-Nitroso(benzyl)methylamine
  • N-Nitroso(methyl)benzylamine
  • n-nitrosobenzylmethylamine
  • n-nitrosomethylbenzylamine
  • N-Nitroso-N-methylbenzenemethanamine
CAS:
937-40-6
MF:
C8H10N2O
MW:
150.18
Mol File:
937-40-6.mol
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BENZYL METHYL NITROSAMINE Chemical Properties

Boiling point:
271.72°C (rough estimate)
Density 
1.1392 (rough estimate)
refractive index 
1.6180 (estimate)
storage temp. 
Refrigerator, Under inert atmosphere
solubility 
Chloroform (Sparingly), Methanol (Slightly)
form 
Oil
pka
-4.77±0.70(Predicted)
color 
Colourless to Pale Yellow
Water Solubility 
4.505g/L(24 ºC)
EPA Substance Registry System
N-Methyl-N-nitrosobenzylamine (937-40-6)
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BENZYL METHYL NITROSAMINE Usage And Synthesis

Uses

N-Nitroso-N-methylbenzylamine induced neoplasia in mice. Mice treated intragastrically with N-Nitroso-N-methylbenzylamine developed multiple tumours. Mice carrying one inactivated Fhit allele (Fhit +?/- mice) are highly susceptible to tumor induction by N-?nitrosomethylbenzylamine.

Safety Profile

Poison by ingestion. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also NITROSAMINES.

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