Cy7.5 Chemical Properties

solubility 

Easily soluble in methanol, DMF and other organic solvents, very soluble in water

form 

Solid

color 

Dark purple to black

Appearance

Dark green solid

ex/em

778/797nm

ε(extinction coefficient)

222000 L⋅mol−1⋅cm−1

Φ(quantum yield)

0.21

InChIKey

ISGPOTXIUFNEFH-UHFFFAOYSA-N

SMILES

CC1(C(N(CCCCCC(=O)O)C2C=CC3=C(C=C(S(O)(=O)=O)C=C3C1=2)S(O)(=O)=O)=CC=CC=CC=CC1C(C2C3=CC(S(O)(=O)=O)=CC(S([O-])(=O)=O)=C3C=CC=2[N+]=1CC)(C)C)C

Cy7.5 Usage And Synthesis

Chemical Properties

Appearance: Dark green solid
ex/em: 778/797nm
Extinction coefficient (ε): 222000 L??mol??1??cm??1
Quantum yield (Φ): 0.21

Uses

Cy7.5 is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis[1]. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance[2].

References

[1] Ptaszek M. Rational design of fluorophores for in vivo applications. Prog Mol Biol Transl Sci. 2013;113:59-108. DOI:10.1016/B978-0-12-386932-6.00003-X
[2] Zhan Y, et al. In Vivo Dual-Modality Fluorescence and Magnetic Resonance Imaging-Guided Lymph Node Mapping with Good Biocompatibility Manganese Oxide Nanoparticles. Molecules. 2017 Dec 12;22(12). pii: E2208. DOI:10.3390/molecules22122208
[3] Shindy, H. A. (2017). Fundamentals in the chemistry of cyanine dyes: A review. Dyes and Pigments, 145, 505–513. doi:10.1016/j.dyepig.2017.06.029

Cy7.5(847180-48-7)Related Product Information

• Cyanine7.5 amine
• Cy7.5-PEG-DSPE
• Cy7.5-CONH-(C1-CONH-C2-Mal)-C4-DOTA
• CY7.5- Fibrinogen
• CY7.5-PEG-NHS MV：3400
• Cyanine7.5 NHS ester
• Cyanine7.5 NHS ester