BA, 3NH4
BA, 3NH4 Basic information
- Product Name:
- BA, 3NH4
- Synonyms:
-
- 3-CARBOXYMETHYL-17-METHOXY-6,18,21-TRIMETHYLDOCOSA-2,4,8,12,18,20-HEPTAENEDIOIC ACID
- BONGKREKIC ACID, TRIAMMONIUM SALT
- BA, 3NH4
- 2,4,8,10,14,18,20-Docosaheptaenedioic acid, 20-[2-(aminooxy)-2-oxoethyl]-6-methoxy-2,5,17-trimethyl-, 1,22-diazanyl ester, (2E,4Z,6R,8Z,10E,14E,17S,18E,20Z)-
- Bongkrekic acid trihydroxyamine ester
- CAS:
- 1177154-51-6
- MF:
- C28H41N3O7
- MW:
- 531.64
- Mol File:
- Mol File
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BA, 3NH4 Chemical Properties
- storage temp.
- -20°C
- form
- Beige to pink lyophilized solid.
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BA, 3NH4 Usage And Synthesis
Uses
Bongkrekic Acid is a natural toxin first isolated from coconut tempeh contaminated with bacteria. It is a polyunsaturated long-chain fatty acid derivative that acts as a potent inhibitor of the mitochondrial adenine nucleotide (ADP/ATP) translocase (Ki < 2 nM). Despite its high affinity, bongkrekic acid has a slow rate of action in intact preparations, as it must permeate the inner mitochondrial membrane to bind the translocase.