KALA
KALA Basic information
- Product Name:
- KALA
- Synonyms:
-
- KALA
- L-Alanine, L-tryptophyl-L-α-glutamyl-L-alanyl-L-lysyl-L-leucyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-L-alanyl-L-lysyl-L-histidyl-L-leucyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-L-lysyl-L-alanyl-L-cysteinyl-L-α-glutamyl-
- KALA - 1 mg
- CAS:
- 187987-64-0
- MF:
- C144H248N40O35S
- MW:
- 3131.87
- Mol File:
- 187987-64-0.mol
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KALA Chemical Properties
- Boiling point:
- 2669.2±65.0 °C(Predicted)
- Density
- 1.231±0.06 g/cm3(Predicted)
- form
- Solid
- color
- White to off-white
- Sequence
- Trp-Glu-Ala-Lys-Leu-Ala-Lys-Ala-Leu-Ala-Lys-Ala-Leu-Ala-Lys-His-Leu-Ala-Lys-Ala-Leu-Ala-Lys-Ala-Leu-Lys-Ala-Cys-Glu-Ala
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KALA Usage And Synthesis
Uses
KALA is an amphiphilic peptide that forms an α-helical structure at physiological pH. KALA modifies a plasmid DNA-encapsulating liposomal membrane and is used as a fusogenic peptide in order to achieve effective liver targeting and transfection of DNA via galactose receptors[1].
References
[1] Naoya Miura, et al. Identification and Evaluation of the Minimum Unit of a KALA Peptide Required for Gene Delivery and Immune Activation. J Pharm Sci. 2017 Oct;106(10):3113-3119. DOI:10.1016/j.xphs.2017.05.014
KALASupplier
Creative Peptides
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Nanjing TGpeptide Biotechnology Co.,Ltd.
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