13,14-DIHYDRO-15-KETO PROSTAGLANDIN A2 Chemical Properties

Boiling point:

510.5±33.0 °C(Predicted)

Density 

1.043±0.06 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

DMF: >75 mg/ml
DMSO: >50 mg/ml
Ethanol: >100 mg/mlPBS (pH 7.2): >2.4 mg/ml

pka

4.75±0.10(Predicted)

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22

Safety Statements 

36

13,14-DIHYDRO-15-KETO PROSTAGLANDIN A2 Usage And Synthesis

Uses

13,14-Dihydro-15-keto-prostaglandin A2 is a product of the non-enzymatic dehydration of 13,14-dihydro-15-keto PGE2. It is further broken down into bicyclo PGE2, which acts as a biomarker for PGE2 synthesis[1].

Definition

ChEBI: 15-Keto-13,14-dihydroprostaglandin A2 is a prostanoid.

References

[1] F A Fitzpatrick, et al. The stability of 13,14-dihydro-15 keto-PGE2. Prostaglandins. 1980 Jun;19(6):917-31. DOI:10.1016/0090-6980(80)90126-4
[2] E. GRANSTRÖM . Chemical instability of 15-keto-13,14-dihydro-PGE2: The reason for low assay reliability[J]. Prostaglandins, 1980, 19 6: Pages 933-957. DOI: 10.1016/0090-6980(80)90127-6

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