T-Peptide
T-Peptide Basic information
- Product Name:
- T-Peptide
- Synonyms:
-
- T-Peptide
- L-Argininamide, N-acetyl-D-valyl-D-glutaminyl-D-isoleucyl-D-valyl-D-tyrosyl-D-lysyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-
- Ac-VQIVYKRRRRRRRRR-NH2
- T-peptide TFA
- CAS:
- 2022956-62-1
- MF:
- C92H171N45O18
- MW:
- 2195.63
- Mol File:
- 2022956-62-1.mol
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T-Peptide Chemical Properties
- Density
- 1.50±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
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T-Peptide Usage And Synthesis
Uses
T-peptide, a Tuftsin analog, can be used for the research of human immunodeficiency virus (HIV) infection. T-peptide prevents cellular immunosuppression and improves survival rate in septic mice. T-peptide also can inhibit the growth of residual tumor cells after surgical resection[1][2].
References
[1] Simpson DM, et, al. Peptide T in the treatment of painful distal neuropathy associated with AIDS: results of a placebo-controlled trial. The Peptide T Neuropathy Study Group. Neurology. 1996 Nov;47(5):1254-9. DOI:10.1212/wnl.47.5.1254
[2] Gao YL, et, al. Tuftsin-derived T-peptide prevents cellular immunosuppression and improves survival rate in septic mice. Sci Rep. 2015 Nov 18;5:16725. DOI:10.1038/srep16725
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