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5-ETHYL-2'-DEOXYURIDINE

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5-ETHYL-2'-DEOXYURIDINE Basic information

Product Name:
5-ETHYL-2'-DEOXYURIDINE
Synonyms:
  • 5-ethyldeoxyuridine
  • aedurid
  • beta-5-ethyldeoxyuridine
  • edoxudin
  • edu
  • 5-Ethyl-durd
  • Aids021723
  • Aids-021723
CAS:
15176-29-1
MF:
C11H16N2O5
MW:
256.26
EINECS:
239-226-1
Mol File:
15176-29-1.mol
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5-ETHYL-2'-DEOXYURIDINE Chemical Properties

Melting point:
152-153°
Density 
1.389±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO (Slightly), Methanol (Slightly, Sonicated), Water (Slightly)
form 
Solid
pka
9.98(at 25℃)
color 
Pale Beige to Beige
biological source
synthetic (organic)
Water Solubility 
water: 50mg/mL, clear, colorless to yellow
Stability:
Hygroscopic
InChI
InChI=1S/C11H16N2O5/c1-2-6-4-13(11(17)12-10(6)16)9-3-7(15)8(5-14)18-9/h4,7-9,14-15H,2-3,5H2,1H3,(H,12,16,17)/t7-,8+,9+/m0/s1
InChIKey
XACKNLSZYYIACO-DJLDLDEBSA-N
SMILES
OC[C@H]1O[C@@H](N2C=C(CC)C(=O)NC2=O)C[C@@H]1O
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Safety Information

WGK Germany 
3
RTECS 
YU7500000
HS Code 
29349990

MSDS

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5-ETHYL-2'-DEOXYURIDINE Usage And Synthesis

Chemical Properties

Edoxudine is solid

Uses

antiallergic, mast cell degranulation inhibitor, angiogenesis blocker

Uses

5-Ethyl-2’-deoxyuridine was found to be a modulator of both antitumor action and pharmacokinetics of 5-Fluorouracil (F596000), a potent antineoplastic agent in clinical use.

Uses

Edoxudine was found to be a modulator of both antitumor action and pharmacokinetics of 5-Fluorouracil (F596000), a potent antineoplastic agent in clinical use.

Definition

ChEBI: Edoxudine is a pyrimidine 2'-deoxyribonucleoside.

Biochem/physiol Actions

5-Ethyl-2′-deoxyuridine (EUdR) is used as a 5-fluorouracil (FU) modulator. EtdUrd may be used to enhance the therapeutic index of 5-FU by reducing the catabolism, prolonging the plasma and intratumoral concentrations of 5-FU, and offering protection to normal organs by increasing the endogenous uridine levels.

5-ETHYL-2'-DEOXYURIDINESupplier

Guangzhou Ribobio Co.,LTD Gold
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020-82119435 18922123670
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18210857532; 18210857532
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021-61551611 13296011611
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contact@trustwe.com
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