5-ETHYL-2'-DEOXYURIDINE
5-ETHYL-2'-DEOXYURIDINE Basic information
- Product Name:
- 5-ETHYL-2'-DEOXYURIDINE
- Synonyms:
-
- 5-ethyldeoxyuridine
- aedurid
- beta-5-ethyldeoxyuridine
- edoxudin
- edu
- 5-Ethyl-durd
- Aids021723
- Aids-021723
- CAS:
- 15176-29-1
- MF:
- C11H16N2O5
- MW:
- 256.26
- EINECS:
- 239-226-1
- Mol File:
- 15176-29-1.mol
5-ETHYL-2'-DEOXYURIDINE Chemical Properties
- Melting point:
- 152-153°
- Density
- 1.389±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMSO (Slightly), Methanol (Slightly, Sonicated), Water (Slightly)
- form
- Solid
- pka
- 9.98(at 25℃)
- color
- Pale Beige to Beige
- Stability:
- Hygroscopic
MSDS
- Language:English Provider:SigmaAldrich
5-ETHYL-2'-DEOXYURIDINE Usage And Synthesis
Chemical Properties
Edoxudine is solid
Uses
antiallergic, mast cell degranulation inhibitor, angiogenesis blocker
Uses
5-Ethyl-2’-deoxyuridine was found to be a modulator of both antitumor action and pharmacokinetics of 5-Fluorouracil (F596000), a potent antineoplastic agent in clinical use.
Uses
Edoxudine was found to be a modulator of both antitumor action and pharmacokinetics of 5-Fluorouracil (F596000), a potent antineoplastic agent in clinical use.
Definition
ChEBI: Edoxudine is a pyrimidine 2'-deoxyribonucleoside.
Biochem/physiol Actions
5-Ethyl-2′-deoxyuridine (EUdR) is used as a 5-fluorouracil (FU) modulator. EtdUrd may be used to enhance the therapeutic index of 5-FU by reducing the catabolism, prolonging the plasma and intratumoral concentrations of 5-FU, and offering protection to normal organs by increasing the endogenous uridine levels.
5-ETHYL-2'-DEOXYURIDINESupplier
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5-ETHYL-2'-DEOXYURIDINE(15176-29-1)Related Product Information
- 5-ETHYL-2'-DEOXYURIDINE
- 5-carboxymethyluridine
- AMINOALLYL DUTP
- AMINOALLYL UTP
- 5-(2-HYDROXYETHYL)-2'-DEOXYURIDINE
- 5-PROPYNYLURIDINE
- (AA-UTP) SODIUM SALT
- 3',5'-DI-O-(P-TOLUOYL)-5-(2-HYDROXYETHYL)-2'-DEOXYURIDINE
- 5-Isopropyl-2'-deoxyuridine (IP5dU)
- 2'β-Fluoro-5-ethyl-2'-deoxyuridine
- 5-ethyl-2'-deoxyuridine triphosphate
- 2'-DEOXY-3',5'-DI-O-(4-METHYLBENZOYL)-5-ETHYLURIDINE
- 5-AMINOALLYL-2'-DEOXYURIDINE-5'-TRIPHOSPHATE LITHIUM SALT
- 5-AMINOALLYLURIDINE-5'-TRIPHOSPHATE LITHIUM SALT
- 2'-FLUORO-2'-ARABINOFURANOSYL-5-ETHYLURACIL, [3H]-
- AURORA KA-627
- 5-[N-(N-BIOTINYL-EPSILON-AMINOCAPROYL)-3-AMINOALLYL]-2'-DEOXYURIDINE-5'-TRIPHOSPHATE
- 5-AMINOALLYL-2'-DEOXYURIDINE