Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-
Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro- Basic information
- Product Name:
- Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-
- Synonyms:
-
- Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-
- 4-chloro-N-[(3R)-quinuclidin-3-yl]benzamide
- PNU 282987 free base
- N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-4-chlorobenzamide
- (R)-4-Chloro-N-(quinuclidin-3-yl)benzamide
- CAS:
- 711085-63-1
- MF:
- C14H17ClN2O
- MW:
- 264.75
- Mol File:
- 711085-63-1.mol
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Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro- Chemical Properties
- Boiling point:
- 431.5±30.0 °C(Predicted)
- Density
- 1.27±0.1 g/cm3(Predicted)
- solubility
- DMF: 10 mg/ml; DMSO: 30 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 5 mg/ml
- form
- A crystalline solid
- pka
- 13.86±0.20(Predicted)
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Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro- Usage And Synthesis
Uses
PNU-282987 is a highly selective α7 nicotinic acetylcholine receptor agonist (1,2). PNU-282,987 has been utilized to generate retinal neurons in the absence of retinal injury or exogenous growth factors in rat (1). PNU-282,987 has the potential to reverse vision loss due to neurodegenerative disease or aging.
Definition
ChEBI: N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-4-chlorobenzamide is a carbonyl compound and an organohalogen compound.
storage
Store at RT
Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-Supplier
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