2',3'-Di-O-acetyl-D-uridine Chemical Properties

Melting point:

142-143 °C

Density 

1.49±0.1 g/cm3(Predicted)

pka

9.39±0.10(Predicted)

2',3'-Di-O-acetyl-D-uridine Usage And Synthesis

Uses

2',3'-Di-O-acetyl-D-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005