Cindunistat ,PF-00572986 PHA-84250
Cindunistat ,PF-00572986 PHA-84250 Basic information
- Product Name:
- Cindunistat ,PF-00572986 PHA-84250
- Synonyms:
-
- Cindunistat ,PF-00572986 PHA-84250
- S-[2-[(1-iminoethyl) amino]ethyl]-2-methyl-L-custeine
- Cindunistat
- (R)-3-((2-Acetimidamidoethyl)thio)-2-amino-2-methylpropanoic acid
- L-Cysteine, S-[2-[(1-iminoethyl)amino]ethyl]-2-methyl-
- CAS:
- 364067-22-1
- MF:
- C8H17N3O2S
- MW:
- 219.3
- Mol File:
- 364067-22-1.mol
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Cindunistat ,PF-00572986 PHA-84250 Chemical Properties
- Boiling point:
- 371.9±52.0 °C(Predicted)
- Density
- 1.27±0.1 g/cm3(Predicted)
- pka
- 2.11±0.10(Predicted)
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Cindunistat ,PF-00572986 PHA-84250 Usage And Synthesis
Uses
Cindunistat (SD-6010) is a potent, orally active and selective iNOS inhibitor[1].
References
[1] Hellio le Graverand MP, et al. A 2-year randomised, double-blind, placebo-controlled, multicentre study of oral selective iNOS inhibitor, cindunistat (SD-6010), in patients with symptomatic osteoarthritis of the knee. Ann Rheum Dis. 2013;72(2):187-195. DOI:10.1136/annrheumdis-2012-202239
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